AUTHOR=Kvedaras Mindaugas , Minderis Petras , Fokin Andrej , Ratkevicius Aivaras , Venckunas Tomas , Lionikas Arimantas TITLE=Forced Running Endurance Is Influenced by Gene(s) on Mouse Chromosome 10 JOURNAL=Frontiers in Physiology VOLUME=8 YEAR=2017 URL=https://www.frontiersin.org/journals/physiology/articles/10.3389/fphys.2017.00009 DOI=10.3389/fphys.2017.00009 ISSN=1664-042X ABSTRACT=
Phenotypic diversity between laboratory mouse strains provides a model for studying the underlying genetic mechanisms. The A/J strain performs poorly in various endurance exercise models. The aim of the study was to test if endurance capacity and contractility of the fast- and slow-twitch muscles are affected by the genes on mouse chromosome 10. The C57BL/6J (B6) strain and C57BL/6J-Chr 10A/J/NaJ (B6.A10) consomic strain which carries the A/J chromosome 10 on a B6 strain background were compared. The B6.A10 mice compared to B6 were larger in body weight (