AUTHOR=Finn Roderick Nigel , Cerdà Joan 

TITLE=Aquaporin Evolution in Fishes

JOURNAL=Frontiers in Physiology

VOLUME=2

YEAR=2011

URL=https://www.frontiersin.org/journals/physiology/articles/10.3389/fphys.2011.00044

DOI=10.3389/fphys.2011.00044

ISSN=1664-042X

ABSTRACT=<p>Aquaporins represent a primordial group of transmembrane solvent channels that have been documented throughout the living biota. This facet alone emphasizes the positive selection pressure for proteins associated with intracellular fluid homeostasis. Amongst extant Eukaryota the highest gene copy number can be found in plants and teleosts, a feature that reflects the genomic duplication history in both groups. In this minireview we discuss the discovery, structure, duplication, and diversification of the aquaporin superfamily. We focus on teleosts as the main models, but include data available for other organisms to provide a broader perspective.</p>