AUTHOR=Cheon Bo-Wi , Min Chul Hee 

TITLE=Prompt gamma imaging system in particle therapy: a mini-review

JOURNAL=Frontiers in Physics

VOLUME=12

YEAR=2024

URL=https://www.frontiersin.org/journals/physics/articles/10.3389/fphy.2024.1356572

DOI=10.3389/fphy.2024.1356572

ISSN=2296-424X

ABSTRACT=<p>Accurate <italic>in-vivo</italic> verification of beam range and dose distribution is crucial for the safety and effectiveness of particle therapy. Prompt gamma (PG) imaging, as a method for real-time verification, has gained prominence in this area. Currently, several PG imaging systems are under development, including gamma electron vertex imaging (GEVI), the Compton camera, the slit camera, and the multi-array type collimator camera. However, challenges persist in dose prediction accuracy, largely due to patient positioning uncertainty and anatomical changes. Although each system demonstrates potential in verifying PG range, further improvements in detection efficiency, spatial resolution, background reduction, and integration into clinical workflows are essential.</p>