Frontiers in Pharmacology

Original Research

Accepted on 17 Feb 2025

Male Mice Treated with Combined Anti-Fibrotic Therapeutics, IPW5371 and Tadalafil, are Predisposed to Adverse Cardiovascular Events

in Translational Pharmacology

Jazz Stephens
Uriel Blas-Machado
Chrissy Sherrill
David Caudell
Nancy Kock
Ashley Davis
Jordyn Whitfield
Barry Hart
Kylie Kavanagh

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1537494

Original Research

Accepted on 17 Feb 2025

Bletilla striata polysaccharide induces autophagy through PI3K/AKT signaling pathway to promote the survival of cross-boundary flap in rats

in Ethnopharmacology

Qin Yue
Xinyi Zeng
Minlan Yang
Jinhao Chen
Lin Liu
Hui Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1544932

Original Research

Accepted on 17 Feb 2025

Targeting Glycolysis in Esophageal Squamous Cell Carcinoma: Single-Cell and Multi-Omics Insights for Risk Stratification and Personalized Therapy

in Drugs Outcomes Research and Policies

Yan Wang
Yunjie Shi
Xiao Hu
Chenfang Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1559546

Review

Accepted on 17 Feb 2025

Recent Advances in the Multifaceted Mechanisms of Catalpol in Treating Osteoporosis

in Experimental Pharmacology and Drug Discovery

Na Li
Xiaoying Mu
Shudong Zhang
Huaxin Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1560715

Original Research

Accepted on 17 Feb 2025

NMN reverses D-galactose-induced neurodegeneration and enhances the intestinal barrier of mice by activating the Sirt1 pathway

in Ethnopharmacology

Yuxian Lin
Yajing Wang
Xinxin Yang
Ziwei Ding
Mingye Hu
Xianfeng Huang
Qichun Zhang
Yingcong Yu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1545585

Original Research

Accepted on 17 Feb 2025

Role of integrin α4 in the inhibition of fibrosis in activated hepatic stellate cells by Periplaneta americana Extract

in Ethnopharmacology

Fang Ying
Ye Liu
chun Ding Li
Yi Miu
xuan Ke Chen
Jv Zhou
juan Li Xie
ting Xi Cheng
yan Jing Wu
Ying Zhu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1517491

Original Research

Accepted on 17 Feb 2025

Bioequivalence of China- and Germany-Manufactured Bisoprolol (Concor®) Tablets in Fasted and Fed Healthy Chinese Participants: A Randomized, Open-Label, Two-Way Crossover Study

in Drug Metabolism and Transport

Hang Yin
Zhili Jin
Ran Li
Dandan Li
Lusha Wang
Ruihua Dong

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1527623

Original Research

Accepted on 17 Feb 2025

Galangin ameliorates PTU-induced vitiligo in zebrafish and B16F10 cells by increasing melanogenesis through activation of the p38/JNK MAPK pathway

in Ethnopharmacology

Zulipikaer Wusiman
Shu-Shu Zhang
Ping-Ping Zhao
Yu-Tong Kang
Yun Zhang
Zhi-Jian Li
Shixia Huo

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1521097

Systematic Review

Accepted on 17 Feb 2025

Effects of Tanreqing injection against Ventilator-associated Pneumonia: a meta-analysis and systematic review of clinical studies

in Ethnopharmacology

POCHEN LI
Yang Wu
Danxia Ge
Ruyi Xu
Qianping Zhang
Yujiao Li
Lingyao Zhang
HsuanChieh Peng
Fangyu Yu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1545088

Clinical Trial

Accepted on 17 Feb 2025

Fuzheng Huayu tablets for treating pulmonary fibrosis in post-COVID-19 patients: A multicenter, randomized, double-blind, placebo-controlled trial

in Ethnopharmacology

Fei Jing
Wei Wang
Jia Ke
Tingrong Huang
Bo Jiang
Qiwu Qiu
Jihan Huang
Songhua Zhan
Zhang Wei
Hui Wu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1508276

Original Research

Accepted on 17 Feb 2025

Non-Chemotherapy Drugs Inducing Agranulocytosis: A Disproportionality Analysis Based on the FAERS Database

in Pharmacoepidemiology

Shanshan Wu
Lina Huang
Jiajia Chen
Xiaochun Xie
Shaokai Huang
Xiaojie Huang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1525307

Review

Accepted on 17 Feb 2025

Efficacy of ginkgo biloba extract in the treatment of idiopathic pulmonary fibrosis: A systematic review and meta-analysis of randomized controlled trials

in Ethnopharmacology

Xuxin Sun
Ling Peng
Wenchao Xiao
Keying Li
Sheng Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1524505

Original Research

Accepted on 17 Feb 2025

FDA-approved drug repurposing screen identifies inhibitors of SARS-CoV-2 pseudovirus entry

in Experimental Pharmacology and Drug Discovery

Manisha Singh
Shruthi Shanmukha
Raghda Eldesouki
Maged M. Harraz

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1537912

Original Research

Accepted on 17 Feb 2025

Predicting protein-protein interactions in microbes associated with cardiovascular disease using deep denoising autoencoders and evolutionary information

in Experimental Pharmacology and Drug Discovery

Yang Li
Senyu Zhou
Jian Luo
Mei Tang
Chaojun Li
Wenhua He

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1565860

Original Research

Accepted on 17 Feb 2025

Metabolomics of the effects of Yishenjiangya granules in older adults with hypertension

in Cardiovascular and Smooth Muscle Pharmacology

Yongbo Ma
Yingying Liu
Li Zhuang
Xia Dai
Li Yao
Jie Yu
Lei Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1491935

Original Research

Accepted on 17 Feb 2025

Semaglutide promotes the proliferation and osteogenic differentiation of bone-derived mesenchymal stem cells through activation of the Wnt/LRP5/β-catenin signaling pathway

in Experimental Pharmacology and Drug Discovery

Yawei Tian
Huiming Liu
Xiaoxue Bao
Yukun Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1539411

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Articles

Male Mice Treated with Combined Anti-Fibrotic Therapeutics, IPW5371 and Tadalafil, are Predisposed to Adverse Cardiovascular Events

Bletilla striata polysaccharide induces autophagy through PI3K/AKT signaling pathway to promote the survival of cross-boundary flap in rats

Targeting Glycolysis in Esophageal Squamous Cell Carcinoma: Single-Cell and Multi-Omics Insights for Risk Stratification and Personalized Therapy

Recent Advances in the Multifaceted Mechanisms of Catalpol in Treating Osteoporosis

NMN reverses D-galactose-induced neurodegeneration and enhances the intestinal barrier of mice by activating the Sirt1 pathway

Role of integrin α4 in the inhibition of fibrosis in activated hepatic stellate cells by Periplaneta americana Extract

Bioequivalence of China- and Germany-Manufactured Bisoprolol (Concor®) Tablets in Fasted and Fed Healthy Chinese Participants: A Randomized, Open-Label, Two-Way Crossover Study

Galangin ameliorates PTU-induced vitiligo in zebrafish and B16F10 cells by increasing melanogenesis through activation of the p38/JNK MAPK pathway

Effects of Tanreqing injection against Ventilator-associated Pneumonia: a meta-analysis and systematic review of clinical studies

Fuzheng Huayu tablets for treating pulmonary fibrosis in post-COVID-19 patients: A multicenter, randomized, double-blind, placebo-controlled trial

Non-Chemotherapy Drugs Inducing Agranulocytosis: A Disproportionality Analysis Based on the FAERS Database

Efficacy of ginkgo biloba extract in the treatment of idiopathic pulmonary fibrosis: A systematic review and meta-analysis of randomized controlled trials

FDA-approved drug repurposing screen identifies inhibitors of SARS-CoV-2 pseudovirus entry

Predicting protein-protein interactions in microbes associated with cardiovascular disease using deep denoising autoencoders and evolutionary information

Metabolomics of the effects of Yishenjiangya granules in older adults with hypertension

Semaglutide promotes the proliferation and osteogenic differentiation of bone-derived mesenchymal stem cells through activation of the Wnt/LRP5/β-catenin signaling pathway