Frontiers in Pharmacology

Original Research

Published on 18 Feb 2025

Potential activity of Ferula macrecolea essential oil for treating Giardia lamblia infection through modulating electrolytes and suppressing NF-κB p65 pathway

in Ethnopharmacology

Iraj Salimikia
Seyed Ehsan Yaghoubi
Amal Khudair Khalaf
Leila Masoori
Javad Ghasemian Yadegari
Hossein Mahmoudvand

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1542425

168 views

Original Research

Published on 18 Feb 2025

Brigatinib can inhibit proliferation and induce apoptosis of human immortalized keratinocyte cells

in Experimental Pharmacology and Drug Discovery

Qi Yang
Dan Zhao
Linjie Ju
Peng Cao
Jifu Wei
Zhixian Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1524277

198 views

Original Research

Accepted on 17 Feb 2025

Adverse event profile of Lomustine and Temozolomide : a descriptive analysis from WHO-VigiAccess

in Experimental Pharmacology and Drug Discovery

Hua Luo
Shaohua Fan
Lu Liang
Youfu He
Jiangjie Chen
Chenghao Xu
Jing Zhu
Liwei Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1534802

Original Research

Accepted on 17 Feb 2025

Sodium nitrate regulates senescence accompanied by aortic atherosclerosis in ApoE -/-mice through the miR-34a/FGF-21 axis

in Translational Pharmacology

Ning Tao
Zhichao He
Han Duan
Liang Wang
Jing Yi
Jingyuan Shao
Lin Lv
Junzhao Duan
Hu Cao
Xiwen Dong

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1562321

Original Research

Accepted on 17 Feb 2025

Berbamine attenuates hind limb ischemia-reperfusion injury by eliminating lipid ROS and inhibiting p65 nuclear translocation

in Ethnopharmacology

Lei Zheng
Biao Zhao
Run Ji
Zhenxi Zhang
Yutong Liu
Xiaoqi Zhao
Jing Cai
Tong Qiao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1509860

Original Research

Accepted on 17 Feb 2025

Exploring the antibacterial potential of Clidemia hirta leaf extract against the pathogenicity of Pseudomonas aeruginosa: in vitro and in silico approaches

in Pharmacology of Infectious Diseases

Vignesh Murugesan
Pargovan Palanivel
Gokul Ramesh
Dwarakesh Ganesh
Helan Soundra Rani Michael
Shivakumar Bandhumy Lingam
Rathish Kumar Sivaraman

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1555542

Original Research

Accepted on 17 Feb 2025

Adverse Event Profiles of EGFR-TKI：Network Meta-analysis and Disproportionality analysis of the FAERS database

in Pharmacology of Anti-Cancer Drugs

Jing Shi
Xinya Liu
Mengjiao Gao
Jian Yu
Ting Chai
Yun Jiang
Jiawei Li
Yuanming Zhang
Li Wu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1519849

Review

Accepted on 17 Feb 2025

Histone deacetylases: the critical enzymes for microglial activation involved in neuropathic pain

in Neuropharmacology

Yi Ding

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1515787

Original Research

Accepted on 17 Feb 2025

α-Bisabolol Alleviates Doxorubicin-Induced Cognitive Dysfunction in Rats Via Enhancing the Hippocampal BDNF/TrKB Signaling and Inhibiting Neuroinflammation

in Neuropharmacology

Sara Taha Elazab
Walter H Hsu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1549009

Original Research

Accepted on 17 Feb 2025

Antimicrobial Photodynamic Therapy with 5-Aminolevulinic Acid plus Antibiotics: A Promising Treatment for Tibial Osteomyelitis Caused by Drug-resistant Bacteria

in Experimental Pharmacology and Drug Discovery

Ju Zuo
Feiyan Kong
Xiyu Wang
Tianyu Wang
Jianxi Zhao
Zhanjuan Zhao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1566744

Original Research

Accepted on 17 Feb 2025

Male Mice Treated with Combined Anti-Fibrotic Therapeutics, IPW5371 and Tadalafil, are Predisposed to Adverse Cardiovascular Events

in Translational Pharmacology

Jazz Stephens
Uriel Blas-Machado
Chrissy Sherrill
David Caudell
Nancy Kock
Ashley Davis
Jordyn Whitfield
Barry Hart
Kylie Kavanagh

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1537494

Original Research

Accepted on 17 Feb 2025

Bletilla striata polysaccharide induces autophagy through PI3K/AKT signaling pathway to promote the survival of cross-boundary flap in rats

in Ethnopharmacology

Qin Yue
Xinyi Zeng
Minlan Yang
Jinhao Chen
Lin Liu
Hui Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1544932

Original Research

Accepted on 17 Feb 2025

Targeting Glycolysis in Esophageal Squamous Cell Carcinoma: Single-Cell and Multi-Omics Insights for Risk Stratification and Personalized Therapy

in Drugs Outcomes Research and Policies

Yan Wang
Yunjie Shi
Xiao Hu
Chenfang Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1559546

Review

Accepted on 17 Feb 2025

Recent Advances in the Multifaceted Mechanisms of Catalpol in Treating Osteoporosis

in Experimental Pharmacology and Drug Discovery

Na Li
Xiaoying Mu
Shudong Zhang
Huaxin Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1560715

Original Research

Accepted on 17 Feb 2025

NMN reverses D-galactose-induced neurodegeneration and enhances the intestinal barrier of mice by activating the Sirt1 pathway

in Ethnopharmacology

Yuxian Lin
Yajing Wang
Xinxin Yang
Ziwei Ding
Mingye Hu
Xianfeng Huang
Qichun Zhang
Yingcong Yu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1545585

Original Research

Accepted on 17 Feb 2025

Role of integrin α4 in the inhibition of fibrosis in activated hepatic stellate cells by Periplaneta americana Extract

in Ethnopharmacology

Fang Ying
Ye Liu
chun Ding Li
Yi Miu
xuan Ke Chen
Jv Zhou
juan Li Xie
ting Xi Cheng
yan Jing Wu
Ying Zhu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1517491

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Articles

Potential activity of Ferula macrecolea essential oil for treating Giardia lamblia infection through modulating electrolytes and suppressing NF-κB p65 pathway

Brigatinib can inhibit proliferation and induce apoptosis of human immortalized keratinocyte cells

Adverse event profile of Lomustine and Temozolomide : a descriptive analysis from WHO-VigiAccess

Sodium nitrate regulates senescence accompanied by aortic atherosclerosis in ApoE -/-mice through the miR-34a/FGF-21 axis

Berbamine attenuates hind limb ischemia-reperfusion injury by eliminating lipid ROS and inhibiting p65 nuclear translocation

Exploring the antibacterial potential of Clidemia hirta leaf extract against the pathogenicity of Pseudomonas aeruginosa: in vitro and in silico approaches

Adverse Event Profiles of EGFR-TKI：Network Meta-analysis and Disproportionality analysis of the FAERS database

Histone deacetylases: the critical enzymes for microglial activation involved in neuropathic pain

α-Bisabolol Alleviates Doxorubicin-Induced Cognitive Dysfunction in Rats Via Enhancing the Hippocampal BDNF/TrKB Signaling and Inhibiting Neuroinflammation

Antimicrobial Photodynamic Therapy with 5-Aminolevulinic Acid plus Antibiotics: A Promising Treatment for Tibial Osteomyelitis Caused by Drug-resistant Bacteria

Male Mice Treated with Combined Anti-Fibrotic Therapeutics, IPW5371 and Tadalafil, are Predisposed to Adverse Cardiovascular Events

Bletilla striata polysaccharide induces autophagy through PI3K/AKT signaling pathway to promote the survival of cross-boundary flap in rats

Targeting Glycolysis in Esophageal Squamous Cell Carcinoma: Single-Cell and Multi-Omics Insights for Risk Stratification and Personalized Therapy

Recent Advances in the Multifaceted Mechanisms of Catalpol in Treating Osteoporosis

NMN reverses D-galactose-induced neurodegeneration and enhances the intestinal barrier of mice by activating the Sirt1 pathway

Role of integrin α4 in the inhibition of fibrosis in activated hepatic stellate cells by Periplaneta americana Extract