Frontiers in Pharmacology

Original Research

Published on 24 Jan 2025

Yunvjian decoction attenuates lipopolysaccharide-induced acute lung injury by inhibiting NF-κB/NLRP3 pathway and pyroptosis

in Ethnopharmacology

Fanxuan Zhang
Fang Wang
Lisha Zhao
Leqian Wang
Wenjing Li
Feihua Huang
Nani Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1430536

709 views

Original Research

Published on 24 Jan 2025

MDTR: a knowledge-guided interpretable representation for quantifying liver toxicity at transcriptomic level

in Predictive Toxicology

Inyoung Sung
Sangseon Lee
Dongmin Bang
Jungseob Yi
Sunho Lee
Sun Kim

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1398370

528 views

Original Research

Published on 24 Jan 2025

Cost-effectiveness analysis of gumarontinib versus savolitinib for the treatment of advanced or metastatic NSCLC with MET exon 14 skipping mutations in China using partitioned survival model

in Drugs Outcomes Research and Policies

Gang Fang
Zhipeng Pi
Yiping An
Xinxin Cao
Wei Li
Xiangjun Zhu
Jinxi Ding

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1400422

529 views

Original Research

Published on 24 Jan 2025

Adverse events of hepatic anti-fibrotic agents in phase 3 and above clinical trials: a descriptive analysis of the WHO-VigiAccess database

in Gastrointestinal and Hepatic Pharmacology

Yuwei Liu
Xu Zhao
Xinrui Wang
Qiang Zhou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1534628

739 views

Original Research

Published on 24 Jan 2025

Self-medication and knowledge of pregnant women about the use of medication during pregnancy in the cities of Rijeka and Zadar, Croatia

in Obstetric and Pediatric Pharmacology

Željko Jovanović
Petra Vulić

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1536050

442 views

Review

Published on 24 Jan 2025

Mini review of plant products as food supplement against MSG-induced liver injury: antioxidant, oxidative stress and histological prospects

in Drug Metabolism and Transport

Dwi Pratiwi Kasmara
Erlina Abdullah
Zaliha Harun
Fatmi Nirmala Sari
Norhashima Abd Rashid
Seong Lin Teoh

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1522814

708 views

Original Research

Published on 24 Jan 2025

Shengxue Busui Decoction activates the PI3K/Akt and VEGF pathways, enhancing vascular function and inhibiting osteocyte apoptosis to combat steroid-induced femoral head necrosis

in Experimental Pharmacology and Drug Discovery

Manting Liu
Jiexiang Ye
Runtian Wu
Dongqiang Luo
Tao Huang
Dandan Dai
Kexin Wang
Yanping Du
Junwen Ou

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1506594

691 views

Review

Published on 24 Jan 2025

Targeting natural antioxidant polyphenols to protect neuroinflammation and neurodegenerative diseases: a comprehensive review

in Ethnopharmacology

Maroua Jalouli
Md Ataur Rahman
Partha Biswas
Hasanur Rahman
Abdel Halim Harrath
In-Seon Lee
Sojin Kang
Jinwon Choi
Moon Nyeo Park
Bonglee Kim

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1492517

1,403 views

Original Research

Published on 24 Jan 2025

Identification of retinol dehydrogenase 10 as a shared biomarker for metabolic dysfunction-associated steatotic liver disease and type 2 diabetes mellitus

in Experimental Pharmacology and Drug Discovery

Fangyu Li
Rui Li
Hongjun Deng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1521416

526 views

Original Research

Published on 24 Jan 2025

Qinggan Yipi capsule ameliorates hepatic fibrosis in rats by down-regulating the TGF-β1/Smad2/3 signaling pathway and improving gut microbiota imbalance

in Ethnopharmacology

Wenjing Xue
Haiqing Liu
Ziheng Su
Siqi Wang
Junping Cheng
Yunzhi Pan
Lurong Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1525914

566 views

Original Research

Published on 24 Jan 2025

Data mining and safety analysis of voriconazole in patients with a hematological malignant tumor based on the FAERS database: differences between children and adults

in Pharmacoepidemiology

Hao Li
Manxue Jiang
Xiaona Pan
Lingti Kong

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1524702

523 views

Review

Published on 24 Jan 2025

Recent advances in polymeric nanoparticles for the treatment of hepatic diseases

in Gastrointestinal and Hepatic Pharmacology

Feng Gao
Xuefei Feng
Xinyu Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1528752

626 views

Review

Accepted on 23 Jan 2025

Medication nonadherence definition, measurement, prevalence, and causes: Reflecting on the past 20 years and looking forwards

in Drugs Outcomes Research and Policies

Sarah C E Chapman
Amy Hai Yan Chan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1465059

Original Research

Published on 23 Jan 2025

hERG activators exhibit antitumor effects in breast cancer through calcineurin and β-catenin-mediated signaling pathways

in Experimental Pharmacology and Drug Discovery

Yan Yu
Chengchun Zhu
Xiao Wang
Ying Shi
Yiping Gao
Zhiyi Yu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1545300

673 views

Original Research

Published on 23 Jan 2025

Chemical characterization and encapsulation of Ganoderma pfeifferi extract with cytotoxic properties

in Experimental Pharmacology and Drug Discovery

Jan Šťastný
Ángela Morellá-Aucejo
Tomáš Skala
Andrea Bernardos
Petr Maršík
Araceli Lérida-Viso
Jaroslav Matějka
Anna Mascellani Bergo
María Dolores Marcos
Ramón Martínez-Máñez

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1526502

413 views

Original Research

Published on 23 Jan 2025

αAsarone alleviates neuronal injury by facilitating autophagy via miR-499-5p/PDCD4/ATG5 signaling pathway in ischemia stroke

in Neuropharmacology

Yonghuan Yan
Linfang Wu
Lu Wang
Dandan Wang
Mengting Huang
Jinyong Peng
Yingying Huang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1504683

587 views

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Articles

Yunvjian decoction attenuates lipopolysaccharide-induced acute lung injury by inhibiting NF-κB/NLRP3 pathway and pyroptosis

MDTR: a knowledge-guided interpretable representation for quantifying liver toxicity at transcriptomic level

Cost-effectiveness analysis of gumarontinib versus savolitinib for the treatment of advanced or metastatic NSCLC with MET exon 14 skipping mutations in China using partitioned survival model

Adverse events of hepatic anti-fibrotic agents in phase 3 and above clinical trials: a descriptive analysis of the WHO-VigiAccess database

Self-medication and knowledge of pregnant women about the use of medication during pregnancy in the cities of Rijeka and Zadar, Croatia

Mini review of plant products as food supplement against MSG-induced liver injury: antioxidant, oxidative stress and histological prospects

Shengxue Busui Decoction activates the PI3K/Akt and VEGF pathways, enhancing vascular function and inhibiting osteocyte apoptosis to combat steroid-induced femoral head necrosis

Targeting natural antioxidant polyphenols to protect neuroinflammation and neurodegenerative diseases: a comprehensive review

Identification of retinol dehydrogenase 10 as a shared biomarker for metabolic dysfunction-associated steatotic liver disease and type 2 diabetes mellitus

Qinggan Yipi capsule ameliorates hepatic fibrosis in rats by down-regulating the TGF-β1/Smad2/3 signaling pathway and improving gut microbiota imbalance

Data mining and safety analysis of voriconazole in patients with a hematological malignant tumor based on the FAERS database: differences between children and adults

Recent advances in polymeric nanoparticles for the treatment of hepatic diseases

Medication nonadherence definition, measurement, prevalence, and causes: Reflecting on the past 20 years and looking forwards

hERG activators exhibit antitumor effects in breast cancer through calcineurin and β-catenin-mediated signaling pathways

Chemical characterization and encapsulation of Ganoderma pfeifferi extract with cytotoxic properties

αAsarone alleviates neuronal injury by facilitating autophagy via miR-499-5p/PDCD4/ATG5 signaling pathway in ischemia stroke