Frontiers in Pharmacology

Clinical Trial

Published on 31 Jan 2025

Yishenyangsui granule for degenerative cervical myelopathy: a randomized, double-blind, placebo-controlled trial with long-term follow-up

in Ethnopharmacology

He Yin
Xin Chen
Zhiwei Liu
Bo Xu
Zhefeng Jin
Yan Liu
Baoyu Qi
Bin Tang
Ping Wang
Fanping Xu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1542231

367 views

Original Research

Published on 31 Jan 2025

Preparation of Tragopogon graminifolius-loaded electrospun nanofibers and evaluating its wound healing activity in a rat model of skin scar

in Experimental Pharmacology and Drug Discovery

Leila Almasi
Elham Arkan
Mohammad Hosein Farzaei
Amin Iranpanah
Cyrus Jalili
Fatemeh Abbaszadeh
Faranak Aghaz
Sajad Fakhri
Javier Echeverría

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1533010

382 views

Original Research

Published on 31 Jan 2025

Immune-related adverse events with PD-1/PD-L1 inhibitors: insights from a real-world cohort of 2523 patients

in Pharmacology of Anti-Cancer Drugs

Ting Yan
Minghui Long
Chaoyi Liu
Jiwen Zhang
Xingyu Wei
Fei Li
Dehua Liao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1519082

430 views

Brief Research Report

Published on 31 Jan 2025

Metformin dosage and galectin-3 levels: insights from PCOS patients preparing for IVF

in Translational Pharmacology

Valentina N. Nikolić
Milan Stefanović
Dejan Mitić
Slavica Sunarić
Vladana Stojiljkovic
Hristina Trajković
Aleksandra Ignjatović
Dragana Stokanović

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1505022

480 views

Systematic Review

Published on 31 Jan 2025

How much can we save by applying artificial intelligence in evidence synthesis? Results from a pragmatic review to quantify workload efficiencies and cost savings

in Drugs Outcomes Research and Policies

Seye Abogunrin
Jeffrey M. Muir
Clarissa Zerbini
Grammati Sarri

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1454245

970 views

Review

Published on 31 Jan 2025

Spatial metabolomics in mental disorders and traditional Chinese medicine: a review

in Ethnopharmacology

Chaofang Lei
Jiaxu Chen
Zhigang Chen
Chongyang Ma
Xudong Chen
Xiongxing Sun
Xukun Tang
Jun Deng
Shiliang Wang
Junlin Jiang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1449639

529 views

Original Research

Published on 31 Jan 2025

Epigallocatechin-3-gallate inhibits the collagen accumulation of oral submucous fibrosis induced by arecoline

in Gastrointestinal and Hepatic Pharmacology

Ge Gao
Caipeng Lin
Ruibo Li
Xi Xie
Hai-Bin Luo

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1540559

279 views

Original Research

Published on 31 Jan 2025

Metallothionein II treatment mitigates rotenone-induced neurodegeneration in zebrafish models of Parkinson’s disease

in Neuropharmacology

Yong Hui Nies
Wei Ling Lim
Norwahidah Abd Karim
Mohamad Fairuz Yahaya
Seong Lin Teoh

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1478013

525 views

Systematic Review

Accepted on 30 Jan 2025

Efficacy and safety of Prunella vulgaris L. combined with antithyroid drugs for hyperthyroidism: A meta-analysis of randomized controlled trials

in Ethnopharmacology

Maoying Wei
Qiyao Zhao
Mingyi Yuan
Yu Yun Fan
Mingdi Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1530152

Original Research

Accepted on 30 Jan 2025

Repurposing Hydrochlorothiazide (HCTZ) for Colorectal Cancer: A Retrospective and Single Center Study

in Pharmacology of Anti-Cancer Drugs

Dominic Chi-Chung Foo
Jiaxi Li
Zheng Huang
Siming Sui
Ryan Wai-Yan Sin
Abraham Man
Wai Lun Law
Lui Ng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1449062

Original Research

Accepted on 30 Jan 2025

Integrated metabolomic and network pharmacology analysis to reveal the mechanisms of Wenshenyang decoction in the treatment of chronic kidney disease

in Renal Pharmacology

Ge JIn
Zongjiang Zhao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1500463

Review

Accepted on 30 Jan 2025

Inflammation Pathways as Therapeutic Targets in Angiotensin II Induced Atrial Fibrillation

in Inflammation Pharmacology

Ailin Hou
Dazhuo Shi
Hongbo Huang
Yuxuan Liu
Ying Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1515864

Original Research

Published on 30 Jan 2025

Mechanism of salvianolic phenolic acids and hawthorn triterpenic acids combination in intervening atherosclerosis: network pharmacology, molecular docking, and experimental validation

in Cardiovascular and Smooth Muscle Pharmacology

Qu Zhai
Shixi Shang
Zihan Zhang
Lihua Sun
Ying Huang
Shuyi Feng
Qian Wu
Haifeng Cui
Xiaolu Shi

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1501846

616 views

Original Research

Published on 30 Jan 2025

Traditional herbal medicine legislative and regulatory framework: a cross-sectional quantitative study and archival review perspectives

in Ethnopharmacology

Sileshi Dubale
Rashed Edris Usure
Yesuneh Tefera Mekasha
Gemmechu Hasen
Firdos Hafiz
Dereje Kebebe
Sultan Suleman

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1475297

889 views

Original Research

Published on 30 Jan 2025

Prediction of traditional Chinese medicine for diabetes based on the multi-source ensemble method

in Experimental Pharmacology and Drug Discovery

Bin Yang
Qingyun Chi
Xiang Li
Jinglong Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1454029

831 views

Clinical Trial

Published on 30 Jan 2025

Comparative evaluation of intravenous versus intranasal dexmedetomidine on emergence delirium and hemodynamics in pediatric patients undergoing adenotonsillectomy: a randomized controlled trial

in Obstetric and Pediatric Pharmacology

Chenxu Dai
Xuemei Zhao
Aoxue Li
Xuedong Zhang
Penglei Wang
Ye Zhang
Yun Wu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1543344

466 views

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Articles

Yishenyangsui granule for degenerative cervical myelopathy: a randomized, double-blind, placebo-controlled trial with long-term follow-up

Preparation of Tragopogon graminifolius-loaded electrospun nanofibers and evaluating its wound healing activity in a rat model of skin scar

Immune-related adverse events with PD-1/PD-L1 inhibitors: insights from a real-world cohort of 2523 patients

Metformin dosage and galectin-3 levels: insights from PCOS patients preparing for IVF

How much can we save by applying artificial intelligence in evidence synthesis? Results from a pragmatic review to quantify workload efficiencies and cost savings

Spatial metabolomics in mental disorders and traditional Chinese medicine: a review

Epigallocatechin-3-gallate inhibits the collagen accumulation of oral submucous fibrosis induced by arecoline

Metallothionein II treatment mitigates rotenone-induced neurodegeneration in zebrafish models of Parkinson’s disease

Efficacy and safety of Prunella vulgaris L. combined with antithyroid drugs for hyperthyroidism: A meta-analysis of randomized controlled trials

Repurposing Hydrochlorothiazide (HCTZ) for Colorectal Cancer: A Retrospective and Single Center Study

Integrated metabolomic and network pharmacology analysis to reveal the mechanisms of Wenshenyang decoction in the treatment of chronic kidney disease

Inflammation Pathways as Therapeutic Targets in Angiotensin II Induced Atrial Fibrillation

Mechanism of salvianolic phenolic acids and hawthorn triterpenic acids combination in intervening atherosclerosis: network pharmacology, molecular docking, and experimental validation

Traditional herbal medicine legislative and regulatory framework: a cross-sectional quantitative study and archival review perspectives

Prediction of traditional Chinese medicine for diabetes based on the multi-source ensemble method

Comparative evaluation of intravenous versus intranasal dexmedetomidine on emergence delirium and hemodynamics in pediatric patients undergoing adenotonsillectomy: a randomized controlled trial