Frontiers in Pharmacology

Original Research

Published on 04 Feb 2025

Impact of fluoxetine exposure on Lymnaea stagnalis and its developing eggs: integrating untargeted lipidomics, targeted metabolomics, and classical risk assessment

in Neuropharmacology

Diana Ilyaskina
Yumi Nakadera
Marja H. Lamoree
Joris M. Koene
Pim E. G. Leonards

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1536438

415 views

Review

Published on 04 Feb 2025

A review on intrathecal administration of medications for leptomeningeal metastases in solid tumors

in Pharmacology of Anti-Cancer Drugs

Xuemei Wang
Chi Yao
Li Quan
Junxiang Zhou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1472945

465 views

Original Research

Accepted on 03 Feb 2025

Exploring Disulfiram Mechanisms in Renal Fibrosis: Insights from Biological Data and Computational Approaches

in Renal Pharmacology

Vishal Patil
Chandragouda R Patil
Harun Patel
Anoop Kumar

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1480732

Original Research

Accepted on 03 Feb 2025

Emodin mitigates rheumatoid arthritis through direct binding to TNF-α

in Ethnopharmacology

Dingyan Lu
Xudong Tian
Taotao Cao
Shuaishuai Chen
Chunhua Liu
Lin Zheng
Meng Zhou
Xiaoyan Peng
Yongjun Li
Ting Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1520281

128 views

Systematic Review

Accepted on 03 Feb 2025

Mulberry Twig Alkaloids for Type 2 Diabetes Mellitus: A System Review and Meta-analysis

in Ethnopharmacology

Yibin Feng
Guoming Chen
Ruifeng Yang
Xiaoya Yang
Jiazhen Jiang
Yudan Guo
Mengshan Xu
Yi Chen
Yining Hou
Cheng Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1475080

114 views

Review

Accepted on 03 Feb 2025

Genome-wide Functional Annotation of Variants: A Systematic Review of State-of-the-Art Tools, Techniques and Resources

in Pharmacogenetics and Pharmacogenomics

Eleftherios Pilalis
Dimitrios Zisis
Christina Andrinopoulou
Theodora Karamanidou
Maria Antonara
Thanos G. Stavropoulos
Aristotelis Chatziioannou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1474026

Mini Review

Accepted on 03 Feb 2025

Bioactive flavonoids metabolites in Citrus species: their potential health benefits and medical potentials

in Ethnopharmacology

Yuqian Xu
Pan He
Beihui He
Zheng Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1552171

Review

Accepted on 03 Feb 2025

The potential of Sijunzi decoction in the fight against gastrointestinal disorders: A review

in Gastrointestinal and Hepatic Pharmacology

Liangjun Yang
Zheng Fang
Jiajie Zhu
Xiaofang Li
Bo Yang
Haiyan Liu
Feiyan Lou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1464498

Original Research

Accepted on 03 Feb 2025

Minding The Gap. Drug-Related Problems among Breastfeeding Women.

in Obstetric and Pediatric Pharmacology

Karolina Morze
Edyta Szałek
Magdalena Waszyk-Nowaczyk

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1542269

Opinion

Accepted on 03 Feb 2025

Two-faced Janus SkQ1/SkQR1: patterns and molecular volume threshold for substrate recognition by the AcrAB-TolC pump

in Drug Metabolism and Transport

Marina V. Karakozova
Alexandra I Sorochkina
Pavel A. Nazarov

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1480955

Review

Accepted on 03 Feb 2025

Natural products modulating MAPK for CRC treatment: a promising strategy

in Ethnopharmacology

Lin Zhou
Jinlong Zhang
Kangning Zhao
Bo Chen
Zhen Sun

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1514486

Original Research

Accepted on 03 Feb 2025

Discovery of highly potent and novel LSD inhibitors for the treatment of acute myeloid leukemia: structure-based virtual screening, molecular dynamics simulation, and biological evaluation

in Experimental Pharmacology and Drug Discovery

Ziyi Hao
Yuting Wang
Xingxia Zhang
Yejun Si
Guoqiang Lin
Shurong Zhang
Miao-Miao Niu
Yanming Zhang
Xiaotian Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1510319

Review

Accepted on 03 Feb 2025

The Role of Neuropeptides in Bone Metabolism and Their Regulation by Anti-Osteoporosis Traditional Chinese Medicine The role of neuropeptides in bone metabolism and related anti-osteoporosis traditional Chinese medicine

in Experimental Pharmacology and Drug Discovery

Qing Lin
Biyi Zhao
Rumeng Chen
Jiajia Huang
Weipeng Sun
Qianyun Ye
Yang Li
Xiaofeng Zhu
Xiaoyun Li
Ronghua Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1516038

102 views

Original Research

Accepted on 03 Feb 2025

Cardioprotective effects of lemon and orange peels and olive oil against doxorubicin-induced myocardial damage in rats

in Ethnopharmacology

Amal El-Refaiy
Zainab A Salem
Abdelnaser A Badawy
Naief Dahran
Mohammed Abu El-Magd

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1506673

Original Research

Accepted on 03 Feb 2025

Small molecule inhibition of ubiquitin C-terminal hydrolase L1 alters cell metabolism proteins and exerts anti-or pro-tumorigenic effects contingent upon chemosensitivity status in high grade serous ovarian cancer

in Pharmacology of Anti-Cancer Drugs

Corinne Jansen
Julia Mcadams
Chloe Kim
Payton De La Cruz
Angelica Salaverria
Nicholas DaSilva
Kathryn Grive
Nicole James

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1547164

Original Research

Published on 03 Feb 2025

Postpartum changes in maternal physiology and milk composition: a comprehensive database for developing lactation physiologically-based pharmacokinetic models

in Obstetric and Pediatric Pharmacology

Neel Deferm
Jean Dinh
Amita Pansari
Masoud Jamei
Khaled Abduljalil

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1517069

691 views

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Articles

Impact of fluoxetine exposure on Lymnaea stagnalis and its developing eggs: integrating untargeted lipidomics, targeted metabolomics, and classical risk assessment

A review on intrathecal administration of medications for leptomeningeal metastases in solid tumors

Exploring Disulfiram Mechanisms in Renal Fibrosis: Insights from Biological Data and Computational Approaches

Emodin mitigates rheumatoid arthritis through direct binding to TNF-α

Mulberry Twig Alkaloids for Type 2 Diabetes Mellitus: A System Review and Meta-analysis

Genome-wide Functional Annotation of Variants: A Systematic Review of State-of-the-Art Tools, Techniques and Resources

Bioactive flavonoids metabolites in Citrus species: their potential health benefits and medical potentials

The potential of Sijunzi decoction in the fight against gastrointestinal disorders: A review

Minding The Gap. Drug-Related Problems among Breastfeeding Women.

Two-faced Janus SkQ1/SkQR1: patterns and molecular volume threshold for substrate recognition by the AcrAB-TolC pump

Natural products modulating MAPK for CRC treatment: a promising strategy

Discovery of highly potent and novel LSD inhibitors for the treatment of acute myeloid leukemia: structure-based virtual screening, molecular dynamics simulation, and biological evaluation

The Role of Neuropeptides in Bone Metabolism and Their Regulation by Anti-Osteoporosis Traditional Chinese Medicine The role of neuropeptides in bone metabolism and related anti-osteoporosis traditional Chinese medicine

Cardioprotective effects of lemon and orange peels and olive oil against doxorubicin-induced myocardial damage in rats

Small molecule inhibition of ubiquitin C-terminal hydrolase L1 alters cell metabolism proteins and exerts anti-or pro-tumorigenic effects contingent upon chemosensitivity status in high grade serous ovarian cancer

Postpartum changes in maternal physiology and milk composition: a comprehensive database for developing lactation physiologically-based pharmacokinetic models