Frontiers in Pharmacology

Original Research

Accepted on 10 Feb 2025

Polydatin combined with hawthorn flavonoids alleviate high fat diet induced atherosclerosis by remodeling the gut microbiota and glycolipid metabolism

in Ethnopharmacology

Dan Li
Yujuan Li
Shengjie Yang
Xiaonan Zhang
Yu Cao
Qiutao Wang
赵冉
Yixi Zhao
Xiao Jin
Jing Lu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1515485

159 views

Original Research

Accepted on 10 Feb 2025

In silico predictions of drug-induced changes in human cardiac contractility agree with experimental recordings

in Cardiovascular and Smooth Muscle Pharmacology

Cristian Trovato
Stefano Longobardi
Elisa Passini
Kylie A. Beattie
Maxx Holmes
Khuram Chaudhary
Eric Rossman
Blanca Rodriguez

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1500668

Review

Accepted on 10 Feb 2025

Effect of Sodium-Glucose Co-Transporter 2 Inhibitors on Coronary Microcirculation

in Cardiovascular and Smooth Muscle Pharmacology

Shaoxin Chen
Weiqian Ou
Shuguang Gan
Lixian Chen
Baohua Liu
Zhenhong Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1523727

Original Research

Accepted on 10 Feb 2025

Development and validation of a prediction model for VTE risk in gastric and esophageal cancer patients

in Cardiovascular and Smooth Muscle Pharmacology

Xingyue Zheng
Liuyun Wu
Lian Li
Yin Wang
Qinan Yin
Lizhu Han
Xingwei Wu
Bian Yuan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1448879

Review

Published on 10 Feb 2025

Research progress of hypoxia-inducible factor-1α and zinc in the mechanism of diabetic kidney disease

in Renal Pharmacology

Wei Qin
Ping Nie
Xuejun Hui
Fei Chen
Xingbao Hu
Wenjiao Shi
Manyu Luo
Bing Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1537749

237 views

Editorial

Published on 10 Feb 2025

Editorial: Ovarian cancer targeted medication: PARP inhibitors, anti-angiogenic drugs, immunotherapy, and more, volume II

in Pharmacology of Anti-Cancer Drugs

Zhi-Bin Wang
De-Hua Liao
Guang Lei
Zhao-Qian Liu
Nayiyuan Wu
Jing Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1552652

242 views

Original Research

Published on 10 Feb 2025

Safety profiles of sevoflurane in pediatric patients: a real-world pharmacovigilance assessment based on the FAERS database

in Obstetric and Pediatric Pharmacology

Chuang Yang
Bangjian Deng
Qiang Wen
Pei Guo
Xiang Liu
Chen Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1548376

228 views

Perspective

Published on 10 Feb 2025

Leveraging AI to optimize vaccines supply chain and logistics in Africa: opportunities and challenges

in Drugs Outcomes Research and Policies

Sulaiman Muhammad Musa
Usman Abubakar Haruna
Lukman Jibril Aliyu
Mubarak Zubairu
Don Eliseo Lucero-Prisno

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1531141

457 views

Review

Published on 10 Feb 2025

The application of procyanidins in diabetes and its complications: a review of preclinical studies

in Ethnopharmacology

Yongchuang Zhang
Mengna Li
Haoyuan Liu
Yongfu Fan
Huan Huan Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1532246

289 views

Original Research

Published on 10 Feb 2025

The development and evaluation of a tublysine-based antibody-drug conjugate with enhanced tumor therapeutic efficacy

in Pharmacology of Anti-Cancer Drugs

Huihui Guo
Hongsheng Xie
Yuanyuan Huang
Junxiang Jia
Xiangfei Kong
Qingliang Yang
Shun Gai
Wenjun Li
Lu Bai
Lingli Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1532104

374 views

Original Research

Published on 10 Feb 2025

Exploring the multi-targeted mechanism of Saikosaponin A in prostate cancer treatment: a network pharmacology and molecular docking approach

in Ethnopharmacology

Genbao Zhu
Zhiming Jiang
Niuping Zhu
Donghui Wang
Tianpeng Guo
Yiqing Meng
Yi Zhu
Kemeng Tan
Mengxue Hu
Heng Tang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1530715

283 views

Original Research

Published on 10 Feb 2025

Salvia deserti Decne., an endemic and rare subshrub from Arabian desert: antidiabetic and antihyperlipidemic effects of leaf hydroethanolic extracts

in Ethnopharmacology

Arbi Guetat
Slimen Selmi
Abdelrhman T. Abdelwahab
Marwa A. Abdelfattah
Abd Ealrhman M. Elhaj
Roaa T. Mogharbel
M. J. A. Abualreish
Abdullah F. Alanazi
Karim Hosni
Naceur Mejri

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1537071

325 views

Original Research

Published on 10 Feb 2025

Mimosapudica L. aqueous extract protects mice against pilocarpine–picrotoxin kindling-induced temporal lobe epilepsy, oxidative stress, and alteration in GABAergic/cholinergic pathways and BDNF expression

in Ethnopharmacology

Hart Mann Alain Youbi Mambou
Simon Pale
Orelien Sylvain Mtopi Bopda
Vanessa Tita Jugha
Nji Seraphin Ombel Musa
Tambong Ako Ojongnkpot
Bertrand Yuwong Wanyu
Raymond Bess Bila
Rashed N. Herqash
Abdelaaty A. Shahat

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1301002

342 views

Review

Published on 10 Feb 2025

A comprehensive review of Schisandrin B’s preclinical antitumor activity and mechanistic insights from network pharmacology

in Pharmacology of Anti-Cancer Drugs

Yanhua Fang
Juan Pan
Piao Wang
Ruoyu Wang
Shanshan Liang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1528533

185 views

Review

Published on 10 Feb 2025

Optimizing therapeutic outcomes: preconditioning strategies for MSC-derived extracellular vesicles

in Experimental Pharmacology and Drug Discovery

Yuqi Song
Fengrui Liang
Weikun Tian
Erin Rayhill
Liping Ye
Xinghan Tian

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1509418

182 views

Editorial

Published on 10 Feb 2025

Editorial: The mechanistic investigation and emerging therapies for Friedreich’s ataxia

in Neuropharmacology

Yina Dong
Vijayendran Chandran
Elisabetta Soragni
David R. Lynch

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1560808

385 views

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Articles

Polydatin combined with hawthorn flavonoids alleviate high fat diet induced atherosclerosis by remodeling the gut microbiota and glycolipid metabolism

In silico predictions of drug-induced changes in human cardiac contractility agree with experimental recordings

Effect of Sodium-Glucose Co-Transporter 2 Inhibitors on Coronary Microcirculation

Development and validation of a prediction model for VTE risk in gastric and esophageal cancer patients

Research progress of hypoxia-inducible factor-1α and zinc in the mechanism of diabetic kidney disease

Editorial: Ovarian cancer targeted medication: PARP inhibitors, anti-angiogenic drugs, immunotherapy, and more, volume II

Safety profiles of sevoflurane in pediatric patients: a real-world pharmacovigilance assessment based on the FAERS database

Leveraging AI to optimize vaccines supply chain and logistics in Africa: opportunities and challenges

The application of procyanidins in diabetes and its complications: a review of preclinical studies

The development and evaluation of a tublysine-based antibody-drug conjugate with enhanced tumor therapeutic efficacy

Exploring the multi-targeted mechanism of Saikosaponin A in prostate cancer treatment: a network pharmacology and molecular docking approach

Salvia deserti Decne., an endemic and rare subshrub from Arabian desert: antidiabetic and antihyperlipidemic effects of leaf hydroethanolic extracts

Mimosapudica L. aqueous extract protects mice against pilocarpine–picrotoxin kindling-induced temporal lobe epilepsy, oxidative stress, and alteration in GABAergic/cholinergic pathways and BDNF expression

A comprehensive review of Schisandrin B’s preclinical antitumor activity and mechanistic insights from network pharmacology

Optimizing therapeutic outcomes: preconditioning strategies for MSC-derived extracellular vesicles

Editorial: The mechanistic investigation and emerging therapies for Friedreich’s ataxia