Frontiers in Pharmacology

Original Research

Accepted on 10 Feb 2025

Post-Marketing Safety Re-evaluation of Placental Peptide Injection in China: A Large-Scale Multicenter Real-World Study

in Drugs Outcomes Research and Policies

Liguang Duan
Feiyue An
Chen Tian
Wen Yan
Jie Chen
Hongyin Zhang
Xiaoguang Liu
Lingjiao Wang
Zhuo Zhang
Binliang Tong

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1541005

Review

Accepted on 10 Feb 2025

Targeting miRNA with Flavonoids: Unlocking Novel Pathways in Cardiovascular Disease Management

in Cardiovascular and Smooth Muscle Pharmacology

Rony Abdi Syahputra
Arya Tjipta Prananda
Princella Halim

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1532986

Review

Accepted on 10 Feb 2025

Effects of Chinese Medicine on Modulating Interleukin-17regulated Macrophages in Coronary Heart Disease

in Cardiovascular and Smooth Muscle Pharmacology

Qing Liu
Peizhong Liu
Qingqing Liu
Chuangpeng Li
Zhen Zhao
Dawei Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1499786

Systematic Review

Accepted on 10 Feb 2025

Factors Influencing the Cost-effectiveness of Novel Oral Anticoagulants Compared to Vitamin K Antagonists in Patients with Atrial Fibrillation: A Systematic Review

in Drugs Outcomes Research and Policies

Yan Li
Xintian Wang
Aixia Ma
Pingyu Chen
Hongchao Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1441754

Technology and Code

Accepted on 10 Feb 2025

Integrating WHO's Digital Adaptation Kit for Antenatal Care into BornFyne-PNMS: Insights from Cameroon

in Drugs Outcomes Research and Policies

Miriam Nkangu
Brice Tangang
Arthur Pessa
Donald Weledji
Pamela Obegu
Mwenya Kasonde
Valery Ngo
Franck Wanda
Ronald Gobina
Odette Kibu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1474999

Original Research

Accepted on 10 Feb 2025

Marked differences in the effects of levetiracetam and its analogue brivaracetam on microglial, astrocytic-and neuronal density in the rat model of kainic acid-induced temporal lobe epilepsy

in Neuropharmacology

Krisztina Kelemen
Máté Sárosi
Ágnes Csüdör
Károly Orbán-Kis
Hanga Kelemen
László Bába
Zsolt Gall
Eszter Horváth
István Katona
Tibor Szilágyi

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1553545

109 views

Original Research

Accepted on 10 Feb 2025

Identification of Glycolysis-Related Gene Signatures for Prognosis and Therapeutic Targeting in Idiopathic Pulmonary Fibrosis

in Inflammation Pharmacology

Han Gao
Zhongyi Sun
Xingxing Hu
Weiwei Song
Yuan Liu
Menglin Zou
Minghui Zhu
Zhenshun Cheng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1486357

Original Research

Accepted on 10 Feb 2025

Exogenous Galectin-9 Prevents Peri-implantitis in Rats by Regulating Macrophage Polarization

in Experimental Pharmacology and Drug Discovery

Lujin Cheng
Xiaowei Ji
Huerxidai Yilihamujiang
Shuya Dong
Long Mei
Guo Lin
Qihan Tang
Zhongcheng Gong

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1533468

Original Research

Accepted on 10 Feb 2025

The association between the gut microbiome and antituberculosis drug-induced liver injury

in Gastrointestinal and Hepatic Pharmacology

Shengfei Pei
Li Yang
Huixia Gao
Yuzhen Liu
Jianhua Lu
Erhei Dai
Chunyan Meng
Fumin Feng
Yuling Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1512815

Original Research

Accepted on 10 Feb 2025

Novel Selective Glucocorticoid Receptor Modulator GRM-01 Demonstrates Dissociation of Anti-inflammatory Effects from Adverse Effects on Glucose and Bone Metabolism

in Experimental Pharmacology and Drug Discovery

Florian Jakob
Stephanie Hennen
MICHAEL GAUTROIS
Feras Khalil
Andrew Lockhart

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1542351

Original Research

Accepted on 10 Feb 2025

A combinatorial screening protocol for identifying novel and highly potent dual-target inhibitor of BRD4 and STAT3 for kidney cancer therapy

in Experimental Pharmacology and Drug Discovery

Shizhu Zhang
Nan Wu
Yifei Geng
Lixia Guan
Miao-Miao Niu
Jindong Li
Lusha Zhu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1560559

Original Research

Accepted on 10 Feb 2025

Model-informed drug development of novel ROCK2 inhibitor TDI01: population pharmacokinetic study and simulation

in Drug Metabolism and Transport

Xiwei Ji
Yimin Cui

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1477607

Original Research

Accepted on 10 Feb 2025

Signal mining and analysis of ripretinib adverse events: a real-world pharmacovigilance analysis based on the FAERS database

in Pharmacology of Anti-Cancer Drugs

Ye Hu
Linlin Zhang
Qineng Gong
Lei Huang
Cunlin Yin
Yang Miao
Hui Wu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1481114

Review

Accepted on 10 Feb 2025

Unleashing the Power of Peptides in Prostate Cancer Immunotherapy: Mechanism, facts and perspectives peptides for targeted therapy and immunological regulation against prostate cancer: Mechanism, facts and perspectives

in Pharmacology of Anti-Cancer Drugs

Xiaoya Li
Fang Yang
Meijing Wang
Xiaopeng Huang
Xin Zeng
Lu Zhou
Sixue Peng
Jingyi Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1478331

Original Research

Accepted on 10 Feb 2025

Gentiopicroside Targeting AKT1 activates HIF-1α/VEGF Axis Promoting Diabetic Ulcer Wound Healing

in Ethnopharmacology

Mingyan Liu
Xinxia Wang
Yao Wu
Jianguo Sun
Zheng Pan
Li Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1506499

Systematic Review

Accepted on 10 Feb 2025

The efficacy and safety of Panax quinquefolius saponin for heart failure: A systematic review and meta-analysis

in Ethnopharmacology

Jing Wang
Tianying Chang
Zheng Liang
Yingzi Cui
Xiaodan Wang
Lisha Wang
Hongguang Jin

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1463609

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Articles

Post-Marketing Safety Re-evaluation of Placental Peptide Injection in China: A Large-Scale Multicenter Real-World Study

Targeting miRNA with Flavonoids: Unlocking Novel Pathways in Cardiovascular Disease Management

Effects of Chinese Medicine on Modulating Interleukin-17regulated Macrophages in Coronary Heart Disease

Factors Influencing the Cost-effectiveness of Novel Oral Anticoagulants Compared to Vitamin K Antagonists in Patients with Atrial Fibrillation: A Systematic Review

Integrating WHO's Digital Adaptation Kit for Antenatal Care into BornFyne-PNMS: Insights from Cameroon

Marked differences in the effects of levetiracetam and its analogue brivaracetam on microglial, astrocytic-and neuronal density in the rat model of kainic acid-induced temporal lobe epilepsy

Identification of Glycolysis-Related Gene Signatures for Prognosis and Therapeutic Targeting in Idiopathic Pulmonary Fibrosis

Exogenous Galectin-9 Prevents Peri-implantitis in Rats by Regulating Macrophage Polarization

The association between the gut microbiome and antituberculosis drug-induced liver injury

Novel Selective Glucocorticoid Receptor Modulator GRM-01 Demonstrates Dissociation of Anti-inflammatory Effects from Adverse Effects on Glucose and Bone Metabolism

A combinatorial screening protocol for identifying novel and highly potent dual-target inhibitor of BRD4 and STAT3 for kidney cancer therapy

Model-informed drug development of novel ROCK2 inhibitor TDI01: population pharmacokinetic study and simulation

Signal mining and analysis of ripretinib adverse events: a real-world pharmacovigilance analysis based on the FAERS database

Unleashing the Power of Peptides in Prostate Cancer Immunotherapy: Mechanism, facts and perspectives peptides for targeted therapy and immunological regulation against prostate cancer: Mechanism, facts and perspectives

Gentiopicroside Targeting AKT1 activates HIF-1α/VEGF Axis Promoting Diabetic Ulcer Wound Healing

The efficacy and safety of Panax quinquefolius saponin for heart failure: A systematic review and meta-analysis