REVIEW article

Front. Pharmacol.

Sec. Ethnopharmacology

Volume 16 - 2025 | doi: 10.3389/fphar.2025.1570818

This article is part of the Research TopicReviews in Ethnopharmacology: 2025View all 14 articles

Paris spp. (Liliaceae): A review of Its Botany, Ethnopharmacology, Phytochemistry, Pharmacological Activities, and Practical Applications

Provisionally accepted
  • 1Dali University, Dali, China
  • 2Hubei University of Chinese Medicine, Wuhan, Hubei Province, China

The final, formatted version of the article will be published soon.

Paris spp., as a traditional medicinal plant, are widely used globally due to their diverse therapeutic properties, including clearing heat and detoxifying, reducing swelling and relieving pain, calming the liver and suppressing convulsions. This review summarizes the research progress of Paris species in the fields of ethnopharmacology, phytochemistry, pharmacological effects, and applications in recent years. The study systematically retrieved information related to the keywords " phytochemistry, " "pharmacology," and "toxicology" from authoritative databases such as CNKI, PubMed, Elsevier, Web of Science, and SpringerLink , using "Paris L." as a keyword to collect research materials related to this genus. During this process, a total of 431 metabolites were isolated and identified, with steroidal saponins being the most abundant. In addition to their medicinal uses, Paris spp. have also been applied in hair care products, cosmetics, and health products. Despite their demonstrated significant pharmacological activities and potential clinical applications, the field of Paris spp. research still faces several challenges. For example, the specific mechanisms of action against certain diseases are not fully understood, and multiple studies have shown that Paris species' extracts may cause adverse reactions and even toxicity. Therefore, further in-depth research and systematic evaluation are needed to promote the safe application and clinical translation of Paris spp..

Keywords: Ethnopharmacology, phytochemistry, Pharmacological activities, Steroidal saponins, Paris L., applications

Received: 04 Feb 2025; Accepted: 14 Apr 2025.

Copyright: © 2025 Ji, Bin, Lian and Bing. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Chen Xu Bing, Dali University, Dali, China

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