AUTHOR=Halabitska Iryna , Petakh Pavlo , Kamyshnyi Oleksandr TITLE=Metformin as a disease-modifying therapy in osteoarthritis: bridging metabolism and joint health JOURNAL=Frontiers in Pharmacology VOLUME=16 YEAR=2025 URL=https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2025.1567544 DOI=10.3389/fphar.2025.1567544 ISSN=1663-9812