AUTHOR=Zhang Zejin , Yan Zhenzhen , Yuan Tao , Zhao Xiaona , Wang Minghui , Liu Guoqing , Gan Lijun , Qin Wei TITLE=PD-1 inhibition disrupts collagen homeostasis and aggravates cardiac dysfunction through endothelial-fibroblast crosstalk and EndMT JOURNAL=Frontiers in Pharmacology VOLUME=16 YEAR=2025 URL=https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2025.1549487 DOI=10.3389/fphar.2025.1549487 ISSN=1663-9812