AUTHOR=Liu Jimin , Zai Xiang , Tian Xiaqing , Li Jiaxuan , Yan Shipeng , Wang Taiyi TITLE=Practical implementation and impact of the 4R principles in ethnopharmacology: Pursuing a more humane approach to research JOURNAL=Frontiers in Pharmacology VOLUME=16 YEAR=2025 URL=https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2025.1543316 DOI=10.3389/fphar.2025.1543316 ISSN=1663-9812