Skip to main content

REVIEW article

Front. Pharmacol.
Sec. Cardiovascular and Smooth Muscle Pharmacology
Volume 16 - 2025 | doi: 10.3389/fphar.2025.1533162

A review of recent advances in anesthetic drugs for patients undergoing cardiac surgery

Provisionally accepted
Yutian Sun Yutian Sun 1Xiangyou Sun Xiangyou Sun 1Haibo Wu Haibo Wu 1Zhaoyang Xiao Zhaoyang Xiao 1Wei Luo Wei Luo 2*
  • 1 Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning Province, China
  • 2 Department of Anesthesia, Second Affiliated Hospital of Dalian Medical University, Dalian, China

The final, formatted version of the article will be published soon.

    Inducing and maintaining general anesthesia requires a diverse set of medications. As of right now, heart surgery anaesthetic management does not adhere to any one standard protocol or set of drugs. To ensure steady circulatory function while providing sufficient sedation, anaesthetic medications are carefully selected for cardiovascular operations. Among the opioids used most often in cardiac surgery, fentanyl, sufentanil, and remifentanil stand out. As a cardiac anesthesiologist, your key responsibilities will be to keep your patient's blood pressure (BP) and oxygen levels stable, reduce the frequency and intensity of ischemia events, and make it easy for them to get off of cardiopulmonary bypass and supplemental oxygen fast. Additionally, new knowledge gaps have been identified as a result of developments in cardiac anaesthetic, which must be addressed. The goal of the most recent developments in cardiac anesthesia has been to decrease risks and increase accuracy in patient outcomes during cardiac surgeries. Furthermore, new methods and tools are contributing to the evolution of cardiovascular anesthesia toward a more dynamic and patient-centered approach, with an eye on boosting safety, decreasing complications, and facilitating better recovery for patients. New medications and methods have emerged in the field of anaesthetic pharmacology, aiming to improve anesthesia management, particularly for patients who have cardiovascular disease. Optimal cardiovascular stability, fewer side effects, and enhanced surgical recovery are the goals of these medications. We have reviewed all the different kinds of cardiac anaesthetic techniques and medications in this research. We have also looked at the many new anaesthetic medicines that have been produced and used for individuals with cardiovascular issues. Next, we covered prospects in the realm of cardiovascular anesthesia and novel anesthetic cardiac drugs.

    Keywords: cardiovascular anesthesia, cardiovascular surgery, New anesthesia drugs, Drug Delivery Systems, cardiac surgery

    Received: 23 Nov 2024; Accepted: 21 Jan 2025.

    Copyright: © 2025 Sun, Sun, Wu, Xiao and Luo. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Wei Luo, Department of Anesthesia, Second Affiliated Hospital of Dalian Medical University, Dalian, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.