AUTHOR=Ji Xiwei , Cui Yimin TITLE=Model-informed drug development of novel ROCK2 inhibitor TDI01: population pharmacokinetic study and simulation JOURNAL=Frontiers in Pharmacology VOLUME=16 YEAR=2025 URL=https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2025.1477607 DOI=10.3389/fphar.2025.1477607 ISSN=1663-9812