AUTHOR=Alqahtani Safar M. TITLE=Discovering broad-spectrum inhibitors for SARS-CoV-2 variants: a cheminformatics and biophysical approach targeting the main protease JOURNAL=Frontiers in Pharmacology VOLUME=16 YEAR=2025 URL=https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2025.1459581 DOI=10.3389/fphar.2025.1459581 ISSN=1663-9812