AUTHOR=Zhang Wenxin , Teng Hongbo , Zhao Tianyi , Eglitis Roberts I. , Wang Xv , Yu Zhengxuan , Qu Shurong , Wang Haijing , Zhao Yaru , Fan Bowen , Liu Shuangli , Zhao Yan TITLE=The chiisanoside derivatives present in the leaves of Acanthopanax sessiliflorus activate autophagy through the LRP6/GSK3β axis and thereafter inhibit oxidative stress, thereby counteracting cisplatin-induced ototoxicity JOURNAL=Frontiers in Pharmacology VOLUME=15 YEAR=2025 URL=https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2024.1518810 DOI=10.3389/fphar.2024.1518810 ISSN=1663-9812