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REVIEW article

Front. Pharmacol.
Sec. Translational Pharmacology
Volume 15 - 2024 | doi: 10.3389/fphar.2024.1513850
This article is part of the Research Topic Pharmaceutical Biomaterials View all 23 articles

Biomaterials-based phototherapy for bacterial infections

Provisionally accepted
Guangzhi Wu Guangzhi Wu Zhuo Xu Zhuo Xu *Yue Yu Yue Yu Zhang Minglei Zhang Minglei Shuaishuai Wang Shuaishuai Wang Shuo Duan Shuo Duan Xilin Liu Xilin Liu
  • Jilin University, Changchun, China

The final, formatted version of the article will be published soon.

    Bacterial infections and antibiotic resistance are global health problems, and current treatments for bacterial infections still rely on the use of antibiotics. Phototherapy based on the use of a photosensitizer has high efficiency, a broad spectrum, strong selectivity, does not easily induce drug resistance, and is expected to become an effective strategy for the treatment of bacterial infections, particularly drug-resistant infections. This article reviews antimicrobial strategies of phototherapy based on photosensitizers, including photodynamic therapy (PDT), photothermal therapy (PTT), and their combination. These methods have significant application potential in combating multi-drugresistant bacterial and biofilm infections, providing an alternative to traditional antibiotics and chemical antibacterial agents.

    Keywords: antibacterial1, phototherapy2, photodynamic therapy3, photothermal therapy4, photoinitiator5

    Received: 19 Oct 2024; Accepted: 18 Nov 2024.

    Copyright: © 2024 Wu, Xu, Yu, Minglei, Wang, Duan and Liu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Zhuo Xu, Jilin University, Changchun, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.