This article is a correction to:
AMPK Activation Alleviates Myocardial Ischemia-Reperfusion Injury by Regulating Drp1-Mediated Mitochondrial Dynamics
Jingxia Du
Hongchao Li2
Gaofeng Liang- 1Pharmacy Department, School of Basic Medical Sciences, Henan University of Science and Technology, Luoyang, China
- 2Pathology Department, School of Basic Medical Sciences, Henan University of Science and Technology, Luoyang, China
A Corrigendum on
AMPK activation alleviates myocardial ischemia-reperfusion injury by regulating Drp1-mediated mitochondrial dynamics
by Du J, Li H, Song J, Wang T, Dong Y, Zhan A, Li Y and Liang G (2022). Front. Pharmacol. 13:862204. doi: 10.3389/fphar.2022.862204
In the published article, there was an error in Figure 3 as published. The fluorescent image for the H/R group in Figure 3A was mis-assigned. The corrected Figure 3 and its caption appear below.
Figure 3
Figure 3. Activation of AMPK protected H9C2 cells from H/R induced injury. (A) Representative fluorescent and flow cytometer images of JC-1 (Green fluorescence represents monomer JC-1, and red fluorescence represents aggregate JC-1). (B) Representative images of mitochondrial ROS levels by flow cytometry. (C) Quantification of the MMP by detecting the red-to-green fluorescence intensity ratio. (D) AICAR decreased the ROS generation in H9C2 cells. (E, F) AICAR decreased the levels of CK and LDH in culture supernatant of H9C2 cells. (G–I) AICAR decreased the mRNA expression of TNF-α, IL-1β, and IL-6 in H9C2 cells. The data were expressed as mean ± SEM (n = 6 per group). **p < 0.01, *p < 0.05 vs. Control group; ▽▽p < 0.01 vs. Control + AICAR group; ##p < 0.01, #p < 0.05 vs. I/R group.
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
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Keywords: AMPK, DRP1, mitochondrial dynamics, myocardial ischemia/reperfusion injury, ROS, inflammatory factors
Citation: Du J, Li H, Song J, Wang T, Dong Y, Zhan A, Li Y and Liang G (2024) Corrigendum: AMPK activation alleviates myocardial ischemia-reperfusion injury by regulating Drp1-mediated mitochondrial dynamics. Front. Pharmacol. 15:1502512. doi: 10.3389/fphar.2024.1502512
Received: 27 September 2024; Accepted: 04 October 2024;
Published: 11 October 2024.
Edited and reviewed by:
Xianwei Wang, Xinxiang Medical University, ChinaCopyright © 2024 Du, Li, Song, Wang, Dong, Zhan, Li and Liang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Jingxia Du, dujingxia2005@163.com; Gaofeng Liang, lgfeng990448@163.com