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EDITORIAL article

Front. Pharmacol.
Sec. Experimental Pharmacology and Drug Discovery
Volume 15 - 2024 | doi: 10.3389/fphar.2024.1495815
This article is part of the Research Topic Modulation of Immune Function: Drug Discovery and Translational Application View all 6 articles

Editorial: Modulation of Immune Function: Drug Discovery and Translational Application

Provisionally accepted
Ruirong Tan Ruirong Tan 1Jun-Ning Zhao Jun-Ning Zhao 2*
  • 1 Sichuan Translational Medicine Center of Chinese Medicine, Sichuan Academy of Traditional Chinese Medicine, Chengdu, Sichuan Province, China
  • 2 Sichuan Academy of Traditional Chinese Medicine, Chengdu, China

The final, formatted version of the article will be published soon.

    inflammation and reducing disease severity (Yin et al., 2021). Lang et al.present an example of traditional medicine's therapeutic potential in immune modulation, focusing on Wuwei Shexiang Pill (WSP). Their research demonstrates that WSP not only ameliorates ankle swelling and inflammatory cell infiltration, but also modulates multiple immune pathways involved in inflammation. By employing an LC-MS-based metabolomics approach, the study identifies key metabolic pathways that WSP influences, offering a comprehensive view of how systemic immune modulation can alleviate inflammatory diseases. This also supports the idea that traditional medicines, when rigorously tested and characterized, can be valuable sources for drug discovery in immune-related conditions.The modulation of immune responses is also crucial in addressing inflammatory diseases such as stroke (Macrez et In conclusion, the articles in this Research Topic offer a diverse and innovative exploration of how modulating immune function can lead to novel therapeutic strategies across a range of diseases. From the integration of traditional medicines with modern pharmacology to the use of artificial intelligence in drug screening, the contributions emphasize the importance of a multidisciplinary approach to drug discovery. These studies provide a roadmap for future research into immune modulation, focusing on the potential of multiomics techniques, AI-driven methodologies, and the refinement of immunotherapy to tackle some of the most challenging diseases of our time. As the field of immune function modulation continues to expand, it is evident that both innovative and traditional approaches will play crucial roles in shaping the future of pharmacological interventions. The articles in this Research Topic exemplify the ongoing efforts to bridge the gap between basic immunology and translational medicine, driving forward the development of more precise, effective therapies for immune-related diseases.

    Keywords: drug, Drug Discovery, immune, Immune Regulation, immune response

    Received: 13 Sep 2024; Accepted: 10 Oct 2024.

    Copyright: © 2024 Tan and Zhao. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Jun-Ning Zhao, Sichuan Academy of Traditional Chinese Medicine, Chengdu, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.