AUTHOR=Lin Yu-Wei , Largajolli Anna , Edwards A. Yin , Cheung S. Y. Amy , Patel Kashyap , Hennig Stefanie TITLE=Impact of using time-averaged exposure metrics on binary endpoints in exposure-response analyses JOURNAL=Frontiers in Pharmacology VOLUME=15 YEAR=2025 URL=https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2024.1487062 DOI=10.3389/fphar.2024.1487062 ISSN=1663-9812