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REVIEW article
Front. Pharmacol.
Sec. Drugs Outcomes Research and Policies
Volume 15 - 2024 |
doi: 10.3389/fphar.2024.1477550
This article is part of the Research Topic Clinical Pharmacist Service Promotes the Improvement of Medical Quality Volume II View all 9 articles
Expert Consensus on the Off-Label Use in China of Drugs for Rare Hematologic Diseases (2024 Edition)
Provisionally accepted
Bo-xin Zhao
1
Xuan Zhou
1*
Ping Zheng
1*
Bo Zhang
2*
Xiaoqin Feng
1
Jie Chen
3
Lisheng Cai
4*
Yilu Chen
5
Liya He
5*
Jianfen Su
6*
Shuqin Cheng
6*
Yingtong Zeng
7*
Guowei Li
8*
Bo Ji
9
Jianlong Wu
4
Weiyi Feng
10*
Maobai Liu
11
Yiran Jin
12
TaoTao Liu
13
Xiaolan Mo
5
Junyan Wu
14*
Hui Wu
15*
Hongliang Zhang
13
Zhichang Zheng
16*
Zhihua Zheng
17*
Jing Sun
1*
Yilei Li
1*- 1 Nanfang Hospital, Southern Medical University, Guangzhou, China
- 2 Peking Union Medical College Hospital (CAMS), Beijing, Beijing Municipality, China
- 3 The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong Province, China
- 4 Shenzhen Second People's Hospital, Shenzhen, Guangdong Province, China
- 5 Guangzhou Women and Children’s Medical Center, Guangzhou Medical University, Guangzhou, Guangdong Province, China
- 6 Guangzhou Panyu Central Hospital, Guangzhou, China
- 7 Guangdong Provincial People's Hospital, Guangzhou, Guangdong Province, China
- 8 Huizhou Central People's Hospital, Huizhou, Guangdong Province, China
- 9 General Hospital of Southern Theater Command of PLA, Southern Medical University, Guangzhou, Guangdong Province, China
- 10 The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China
- 11 Fujian Medical University Union Hospital, Fuzhou, Fujian Province, China
- 12 Second Hospital of Hebei Medical University, Shijiazhuang, Hebei Province, China
- 13 First Affiliated Hospital, Guangxi Medical University, Nanning, Guangxi Zhuang Region, China
- 14 Sun Yat-sen Memorial Hospital, Guangzhou, Guangdong Province, China
- 15 The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province, China
- 16 Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou Province, China
- 17 Guangdong Pharmaceutical Association, Guangzhou, China
Drug package inserts are a crucial foundation for clinical medication practices and serve as the legal basis for guiding rational drug use and ensuring patient safety and efficacy. As rare disease treatments evolve, current package inserts often need to meet the clinical requirements for treating such conditions, frequently resulting in off-label drug use. This consensus is derived from discussions between Guangdong Pharmaceutical Association Hematologic Rare Diseases Group experts. The consensus aims to provide a framework and reference for the clinical application of off-label drug use in treating rare hematologic diseases.
Keywords: Rare Diseases, Hematological disease, off-label drug use, expert consensus, evidencebased pharmacy
Received: 08 Aug 2024; Accepted: 17 Sep 2024.
Copyright: © 2024 Zhao, Zhou, Zheng, Zhang, Feng, Chen, Cai, Chen, He, Su, Cheng, Zeng, Li, Ji, Wu, Feng, Liu, Jin, Liu, Mo, Wu, Wu, Zhang, Zheng, Zheng, Sun and Li. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Xuan Zhou, Nanfang Hospital, Southern Medical University, Guangzhou, China
Ping Zheng, Nanfang Hospital, Southern Medical University, Guangzhou, China
Bo Zhang, Peking Union Medical College Hospital (CAMS), Beijing, 100730, Beijing Municipality, China
Lisheng Cai, Shenzhen Second People's Hospital, Shenzhen, Guangdong Province, China
Liya He, Guangzhou Women and Children’s Medical Center, Guangzhou Medical University, Guangzhou, 510623, Guangdong Province, China
Jianfen Su, Guangzhou Panyu Central Hospital, Guangzhou, China
Shuqin Cheng, Guangzhou Panyu Central Hospital, Guangzhou, China
Yingtong Zeng, Guangdong Provincial People's Hospital, Guangzhou, 510317, Guangdong Province, China
Guowei Li, Huizhou Central People's Hospital, Huizhou, 516001, Guangdong Province, China
Weiyi Feng, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, Shaanxi, China
Junyan Wu, Sun Yat-sen Memorial Hospital, Guangzhou, 510000, Guangdong Province, China
Hui Wu, The First Affiliated Hospital of Kunming Medical University, Kunming, 650032, Yunnan Province, China
Zhichang Zheng, Affiliated Hospital of Guizhou Medical University, Guiyang, 550004, Guizhou Province, China
Zhihua Zheng, Guangdong Pharmaceutical Association, Guangzhou, China
Jing Sun, Nanfang Hospital, Southern Medical University, Guangzhou, China
Yilei Li, Nanfang Hospital, Southern Medical University, Guangzhou, China
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