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REVIEW article

Front. Pharmacol.
Sec. Integrative and Regenerative Pharmacology
Volume 15 - 2024 | doi: 10.3389/fphar.2024.1476670

Phytochemicals, promising strategies combating Cutibacterium acnes

Provisionally accepted
Cuilian Sun Cuilian Sun 1*Yuhang Na Yuhang Na 1*Ziyu Wang Ziyu Wang 2*Tingting Zhu Tingting Zhu 3*Xiaojuan Liu Xiaojuan Liu 1*
  • 1 Department of Pathogen Biology, Medical College, Nantong University, Jiangsu, China, Nantong, Jiangsu, China
  • 2 Medical College, Nantong University, Jiangsu, China, Nantong, Jiangsu, China
  • 3 Department of Dermatology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province, China

The final, formatted version of the article will be published soon.

    The excessive proliferation of Cutibacterium acnes (C. acnes) is an important reason for the occurrence of acne vulgaris, and genetic detection ratio of C. acnes in acne is as high as 60.5%. Until now, the treatment of C. acnes is mainly limited to antibiotics, but some strains of C. acnes produce antimicrobial resistances, making it difficult for clinical treatment. Additionally, antibiotics can cause severe adverse effects.Therefore, more and more people are paying attention to phytochemicals.It is well known that plants can synthesize a range of secondary metabolites, named phytochemicals, part of which have antibacterial properties. Additionally, the main advantages of phytochemicals are that they have good efficacies and less side effects, so they are suitable choices for medical treatment. This review mainly discusses the effects and mechanisms of phytochemicals against C. acnes.

    Keywords: Cutibacterium acnes, Acne Vulgaris, phytochemicals, Plant composition, Antibiosis

    Received: 06 Aug 2024; Accepted: 25 Nov 2024.

    Copyright: © 2024 Sun, Na, Wang, Zhu and Liu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Cuilian Sun, Department of Pathogen Biology, Medical College, Nantong University, Jiangsu, China, Nantong, Jiangsu, China
    Yuhang Na, Department of Pathogen Biology, Medical College, Nantong University, Jiangsu, China, Nantong, Jiangsu, China
    Ziyu Wang, Medical College, Nantong University, Jiangsu, China, Nantong, Jiangsu, China
    Tingting Zhu, Department of Dermatology, The First Affiliated Hospital of Soochow University, Suzhou, 215006, Jiangsu Province, China
    Xiaojuan Liu, Department of Pathogen Biology, Medical College, Nantong University, Jiangsu, China, Nantong, Jiangsu, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.