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REVIEW article

Front. Pharmacol.
Sec. Experimental Pharmacology and Drug Discovery
Volume 15 - 2024 | doi: 10.3389/fphar.2024.1438227

Advancing Biomedical Applications: An In-Depth Analysis of Silver Nanoparticles in Antimicrobial, Anticancer, and Wound Healing Roles

Provisionally accepted
Avtar Singh Avtar Singh 1*Himanshu Jangid Himanshu Jangid 2Sudhakar Singh Sudhakar Singh 2Piyush Kashyap Piyush Kashyap 3Gaurav Kumar Gaurav Kumar 2*
  • 1 Adama Science and Technology University, Adama, Ethiopia
  • 2 School of Bioengineering and Biosciences, Lovely Professional University, Phagwara, Punjab, India
  • 3 Department of Food Technology, School of Agriculture, Lovely Professional University, Phagwara, Punjab, India

The final, formatted version of the article will be published soon.

    This review offers a comprehensive examination of the scientific progression involving silver nanoparticles (AgNPs) within three key biomedical domains: their antimicrobial characteristics, potential for anticancer applications, and effectiveness in wound healing. By thoroughly analyzing literature spanning two decades, it evaluates the academic contributions, citation patterns, collaborative endeavors, and evolving subjects within each application field. The escalating number of publications focusing on the antimicrobial attributes of AgNPs underscores the global imperative to combat antibiotic resistance. In the domain of anticancer investigation, there has been a consistent advancement, concentrating on the cytotoxic impact of AgNPs and their ability to induce apoptosis in cancerous cells. Regarding wound healing, the incorporation of AgNPs into innovative dressings demonstrates their dual functionality in fostering tissue regeneration and averting infections. Examination of research output indicates that India and China lead in driving innovation, producing significant citations, thus underscoring the substantial impact and significance of their contributions worldwide. The review identifies enduring and emerging topics, such as the proliferation of "green synthesis" techniques in nanoparticle fabrication, illustrating the field's shift towards sustainability. The insights provided in this paper aim to guide and motivate current and future research endeavors, positioning silver nanoparticles as a crucial component in the advancement of next-generation medical interventions.

    Keywords: silver nanoparticles, antimicrobial resistance, Cancer Nano therapy, Wound Healing Innovations, Sustainable Synthesis Methods and Bibliometric Trend Analysis

    Received: 25 May 2024; Accepted: 26 Jul 2024.

    Copyright: © 2024 Singh, Jangid, Singh, Kashyap and Kumar. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Avtar Singh, Adama Science and Technology University, Adama, Ethiopia
    Gaurav Kumar, School of Bioengineering and Biosciences, Lovely Professional University, Phagwara, 144411, Punjab, India

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.