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ORIGINAL RESEARCH article

Front. Pharmacol.
Sec. Drugs Outcomes Research and Policies
Volume 15 - 2024 | doi: 10.3389/fphar.2024.1420914

Impact of multifaceted interventions on the knowledge, attitude, and practice of adverse drug reactions reporting among healthcare workers in Vietnam: a comparative intervention study

Provisionally accepted
Tham Pham Hong Tham Pham Hong 1Minh-Thy Tran Doan Minh-Thy Tran Doan 2Thuy Dang Thi Thuy Dang Thi 3Dung Nguyen Tuan Dung Nguyen Tuan 3Minh-Hoang Tran Minh-Hoang Tran 4*Thao N. Nguyen Thao N. Nguyen 3*
  • 1 Department of Pharmacy, Nguyen Tat Thanh University, Ho Chi Minh City, Vietnam
  • 2 Department of Pharmacy, Nhan Dan Gia Dinh Hospital, Ho Chi Minh City, Vietnam
  • 3 Faculty of Pharmacy, Ho Chi Minh City Medicine and Pharmacy University, Ho Chi Minh City, Vietnam
  • 4 NTT Hi-Tech Institute, Nguyen Tat Thanh University, Hồ Chí Minh, Vietnam

The final, formatted version of the article will be published soon.

    Knowledge, attitude, and practice of Adverse Drug Reactions (ADRs) and ADRs reporting among healthcare workers were related to the quality and ADRs reporting rate. The aim of this study was to evaluate the effectiveness of the multifaceted interventions on knowledge, attitude, and practice (KAP) of healthcare workers and to compare the proportion of spontaneous ADRs reports at the study center, before and after instituting multifaceted interventions.A comparative intervention study was conducted among healthcare workers at the hospital. The participants were asked to complete a questionnaire before and after instituting the multifaceted interventions to assess the KAP of ADRs and their reporting. The impact of the multifaceted interventions was assessed by comparing their correct responses to the KAP questions and the proportion of spontaneous ADRs reports before and after the interventions. The pre-and postintervention scores for KAP questions were compared usingMcNemar test by R Language. 388 healthcare workers completed the study. The proportion of participants qualified for ADRs reporting increased significantly, from 73.5% (pre -intervention) to 99.2% (postintervention) for knowledge scores, from 70.6% to 91.8% for attitude scores, and from 81.4% to 97.2% for practice scores (p < 0.001). Similarly, the number of spontaneous ADRs reports increased by 31% after 3 months of interventions.Multifaceted interventions instituted at the study center improved the knowledge, attitude, and practice of health workers towards ADRs and spontaneous reporting. It would be beneficial to implement such interventions in other hospitals in Vietnam.

    Keywords: adverse drug reactions, KAP, Healthcare workers, Multifaceted interventions, Vietnam

    Received: 21 Apr 2024; Accepted: 29 Oct 2024.

    Copyright: © 2024 Pham Hong, Tran Doan, Dang Thi, Nguyen Tuan, Tran and Nguyen. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Minh-Hoang Tran, NTT Hi-Tech Institute, Nguyen Tat Thanh University, Hồ Chí Minh, Vietnam
    Thao N. Nguyen, Faculty of Pharmacy, Ho Chi Minh City Medicine and Pharmacy University, Ho Chi Minh City, Vietnam

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.