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REVIEW article

Front. Pharmacol.
Sec. Gastrointestinal and Hepatic Pharmacology
Volume 15 - 2024 | doi: 10.3389/fphar.2024.1415011

Effects of perioperative steroid use on surgical stress and prognosis in patients undergoing hepatectomy: a systematic review and meta-analysis of randomized controlled trials

Provisionally accepted
Furui Zhong Furui Zhong Hua Yang Hua Yang *Xuefeng Peng Xuefeng Peng *Kerui Zeng Kerui Zeng *
  • Zigong Fourth People's Hospital, Zigong, China

The final, formatted version of the article will be published soon.

    The objective of this study was to evaluate the clinical effects of perioperative steroid hormone usage in hepatectomy patients through a comprehensive systematic review and meta-analysis. Prospective randomized controlled trials (RCTs) investigating the perioperative use of steroid hormones in hepatectomy were systematically searched using various databases including PubMed, Medline, Embase, Cochrane library, Chinese Biomedical Literature Database, Wanfang Database, and CNKI database. Two researchers independently screened and extracted data from selected studies. Data analysis was performed using RevMan 5.3 software. The results revealed significantly lower levels of total bilirubin (SMD=-0.7; 95%

    Keywords: steroid, Hepatectomy, surgical stress, prognosis, Meta-analysis

    Received: 16 Apr 2024; Accepted: 29 Jul 2024.

    Copyright: © 2024 Zhong, Yang, Peng and Zeng. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Hua Yang, Zigong Fourth People's Hospital, Zigong, China
    Xuefeng Peng, Zigong Fourth People's Hospital, Zigong, China
    Kerui Zeng, Zigong Fourth People's Hospital, Zigong, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.