AUTHOR=Chen Liuping , Chen Huiqi , Guo Sien , Chen Zhijun , Yang Haifeng , Liu Yanjiao , Chen Xiaoling , Chen Xinming , Du Tingting , Long Xinyao , Zhao Jiaxiong , Guo Mingli , Lao Tianfeng , Huang DongHui , Wang Lei , Chen Jing , Liu Chunping TITLE=Psoriasis comorbid with atherosclerosis meets in lipid metabolism JOURNAL=Frontiers in Pharmacology VOLUME=14 YEAR=2023 URL=https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2023.1308965 DOI=10.3389/fphar.2023.1308965 ISSN=1663-9812 ABSTRACT=

Psoriasis (PSO) is a common skin disease affecting approximately 1%–3% of the population, and the incidence rate is increasing yearly. PSO is associated with a dramatically increased risk of cardiovascular disease, the most common of which is atherosclerosis (AS). In the past, inflammation was considered to be the triggering factor of the two comorbidities, but in recent years, studies have found that lipid metabolism disorders increase the probability of atherosclerosis in patients with psoriasis. In this review, we discuss epidemiological studies, clinical treatment methods, risk factors, and lipid metabolism of psoriasis and atherosclerosis comorbidities.