AUTHOR=Takei Sella , Kinoshita Hiroshi , Kumihashi Mitsuru , Jamal Mostofa , Abe Hiroko , Kimura Shoji TITLE=Case report: An autopsy case of pilsicainide poisoning JOURNAL=Frontiers in Pharmacology VOLUME=14 YEAR=2023 URL=https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2023.1090265 DOI=10.3389/fphar.2023.1090265 ISSN=1663-9812 ABSTRACT=

We present a fatal case of pilsicainide poisoning. Quantitative toxicological analysis revealed that the concentrations of pilsicainide in femoral blood and urine samples were 17.5 μg/mL and 136.9 μg/mL, respectively. No morphological changes due to poisoning were observed. Based on the autopsy findings, results of the toxicological examination, and investigation by the authorities, we concluded that the cause of death was due to pilsicainide poisoning.