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CORRECTION article

Front. Pharmacol., 15 August 2022
Sec. Ethnopharmacology
Volume 13 - 2022 | https://doi.org/10.3389/fphar.2022.948569
This article is part of the Research Topic Herbal Medicines for Gastrointestinal and Hepatic Diseases - Novel Pharmacological and Toxicological approaches, Volume I View all 16 articles

Corrigendum: Polysaccharides of Dendrobium officinale Kimura & Migo leaves protect against ethanol-induced gastric mucosal injury via the AMPK/mTOR signaling pathway in vitro and vivo

This article is a correction to:

  1. Polysaccharides of Dendrobium officinale Kimura & Migo Leaves Protect Against Ethanol-Induced Gastric Mucosal Injury via the AMPK/mTOR Signaling Pathway in Vitro and vivo

    1. Read original article
Yang Ke&#x;Yang Ke1†Lianghui Zhan&#x;Lianghui Zhan1†Tingting LuTingting Lu1Cong ZhouCong Zhou1Xue ChenXue Chen1Yingjie DongYingjie Dong1Guiyuan Lv Guiyuan Lv2*Suhong Chen Suhong Chen1*
  • 1Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou, Zhejiang, China
  • 2College of Pharmaceutical Science, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China

A Corrigendum on
Polysaccharides of Dendrobium officinale Kimura & Migo leaves protect against ethanol-induced gastric mucosal injury via the AMPK/mTOR signaling pathway in vitro and vivo

by Ke Y, Zhan L, Lu T, Zhou C, Chen X, Dong Y, Lv G and Chen S (2020). Front. Pharmacol. 11:526349. doi: 10.3389/fphar.2020.526349

In the original article, there was a mistake in Figures 4D, 8D, 10H, 11D as published. Due to the negligence of the author in the drawing process, the pictures are placed repeatedly. The corrected Figures 4, 8, 10, 11 appears below.

FIGURE 4
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FIGURE 4. Effects of LDOP-1 on oxidative stress. ROS (A), SOD (B) and T-AOC (C) were measured by biochemical Assays and the expression of HO-1 (D) was examined by immunohistochemical analysis (400×, brown yellow granules indicate positive reaction). Data are expressed as the mean ± SD of three independent experiments. #p < 0.05, ##p < 0.01 compare the control group; *p < 0.05 and **p < 0.01, ***p < 0.001 compare model group. LDOP-L stood for LDOP-1-L, LDOP-H stood for LDOP-1-H.

FIGURE 8
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FIGURE 8. Effects of LDOP-1 on the production of SOD, T-AOC and ROS. (A–C) The levels of SOD, T-AOC and ROS were measured using a biochemical markers kit. The expression of ROS was detected by Immunofluorescence technique (D). Data are expressed as the mean ± SD of three independent experiments. #p < 0.05, ##p < 0.01, ###p < 0.001 compare the control group; *p < 0.05 and **p < 0.01, ***p < 0.001 compare model group. LDOP stood for LDOP-1.

FIGURE 10
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FIGURE 10. LDOP could activate the autophagy by mTOR/AMPK signaling way in vitro. (A) The expression of LC3β, HO-1, Becline-1, p-AMPK, p62, p-mTOR detected by Western blot. (B–G) Statistical analysis on LC3β, HO-1, Becline-1, p-AMPK, p62, p-mTOR. Immunohistochemical image of HO-1 (H) measured by immunofluorescence technique. Data are expressed as the mean ± SD of three independent experiments. #p < 0.05, ##p < 0.01, ###p < 0.001 compare the control group; *p < 0.05 and **p < 0.01, ***p < 0.001 compare model group, $p < 0.05, $$p < 0.01, $$$p < 0.001 compared with LDOP group.

FIGURE 11
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FIGURE 11. LDOP inhibited the expression of Bax, caspase 3 and boost of Bcl-2. (A) The expression of Bax and Bcl2 detected by Western blot. (B) Statistical analysis on ratio of Bax to Bcl-2. (C) The production of caspase 3 detected by biochemical markers kit. (D) Immunohistochemical image of Bcl2 measured by immunofluorescence technique. Data are expressed as the mean ± SD of three independent experiments. #p < 0.05, ##p < 0.01, ###p < 0.001 compare the control group; *p < 0.05 and **p < 0.01, ***p < 0.001 compare model group.

The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.

Publisher’s note

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.

Keywords: Dendrobium officinale Kimura & Migo leaves (LDOP), polysaccharides, alcohol, gastric injury, autophagy

Citation: Ke Y, Zhan L, Lu T, Zhou C, Chen X, Dong Y, Lv G and Chen S (2022) Corrigendum: Polysaccharides of Dendrobium officinale Kimura & Migo leaves protect against ethanol-induced gastric mucosal injury via the AMPK/mTOR signaling pathway in vitro and vivo. Front. Pharmacol. 13:948569. doi: 10.3389/fphar.2022.948569

Received: 20 May 2022; Accepted: 18 July 2022;
Published: 15 August 2022.

Edited and reviewed by:

Claudio Ferrante, University of Studies G. d’Annunzio Chieti and Pescara, Italy

Copyright © 2022 Ke, Zhan, Lu, Zhou, Chen, Dong, Lv and Chen. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

*Correspondence: Guiyuan Lv, zjtcmlgy@163.com; Suhong Chen, chensuhong@zjut.edu.cn

†These authors have contributed equally to this work and share first authorship

Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.