AUTHOR=Nakae Hajime , Irie Yasuhito , Kitamura Toshiharu , Okuyama Manabu 

TITLE=Application of Traditional Japanese Drug Jidabokuippo in a Modern Society

JOURNAL=Frontiers in Pharmacology

VOLUME=13

YEAR=2022

URL=https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2022.853012

DOI=10.3389/fphar.2022.853012

ISSN=1663-9812

ABSTRACT=<p><bold>Background:</bold> Jidabokuippo (JDI) (治打撲一方) has been used in Japan to alleviate contusion-induced swelling and pain since medieval times.</p><p><bold>Method:</bold> This review investigated the effects of JDI on various symptoms in patients with trauma or static blood<sup>[TM1]</sup>. The PubMed and Igaku Chuo Zasshi databases were searched until 24 December 2021. We summarize the benefits of applying JDI to inflammatory conditions, including bruises.</p><p><bold>Results:</bold> JDI has been used to resolve blood <sup>[TM1]</sup> stasis, regulate qi in trauma patients, and treat inflammatory swelling and pain caused by rheumatoid arthritis and cellulitis. As the adverse event rate associated with JDI is low (1.3%), JDI is considered a safe drug.</p><p><bold>Conclusion:</bold> JDI can be used to resolve blood<sup>[TM1]</sup> stasis in trauma patients without adverse events associated with nonsteroidal anti-inflammatory drugs.</p>