AUTHOR=Xia Lei , Ding Shichao , Wang Xuezhen , Zhang Xiaoyu , Zhu Lin , Zhang Hairong , Li Huirong TITLE=Advances in ovarian cancer treatment using a combination of statins with other drugs JOURNAL=Frontiers in Pharmacology VOLUME=13 YEAR=2023 URL=https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2022.1048484 DOI=10.3389/fphar.2022.1048484 ISSN=1663-9812 ABSTRACT=
New anti-cancer drugs are constantly being developed, especially targeted drugs. Although these drugs have achieved significant clinical efficacy, they do not play a significant role in ovarian cancer. Moreover, the research cycle and costs of such drugs are often huge. The repositioning of conventional drugs has gradually become a concern. Statins, as traditional lipid-lowering drugs, play a role mainly by inhibiting HMGCR. In recent years, epidemiological studies and