AUTHOR=Lu Meng , Lan Xintian , Wu Xi , Fang Xiaoxue , Zhang Yegang , Luo Haoming , Gao Wenyi , Wu Donglu TITLE=Salvia miltiorrhiza in cancer: Potential role in regulating MicroRNAs and epigenetic enzymes JOURNAL=Frontiers in Pharmacology VOLUME=13 YEAR=2022 URL=https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2022.1008222 DOI=10.3389/fphar.2022.1008222 ISSN=1663-9812 ABSTRACT=
MicroRNAs are small non-coding RNAs that play important roles in gene regulation by influencing the translation and longevity of various target mRNAs and the expression of various target genes as well as by modifying histones and DNA methylation of promoter sites. Consequently, when dysregulated, microRNAs are involved in the development and progression of a variety of diseases, including cancer, by affecting cell growth, proliferation, differentiation, migration, and apoptosis. Preparations from the dried root and rhizome of