AUTHOR=Zhang Yao , Chen Yu , Wan Yue , Zhao Yueshui , Wen Qinglian , Tang Xiaolong , Shen Jing , Wu Xu , Li Mingxing , Li Xiang , Li Jing , Li Wanping , Xiao Zhangang , Du Fukuan TITLE=Circular RNAs in the Regulation of Oxidative Stress JOURNAL=Frontiers in Pharmacology VOLUME=12 YEAR=2021 URL=https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2021.697903 DOI=10.3389/fphar.2021.697903 ISSN=1663-9812 ABSTRACT=

Oxidative stress caused by an imbalance between the production and elimination of reactive metabolites and free radicals can lead to the development of a variety of diseases. Over the past years, with the development of science and technology, circular RNA (circRNA) has been found to be closely associated with oxidative stress, which plays an important role in the process of oxidative stress. Currently, the understanding of circRNAs in the mechanism of oxidative stress is limited. In this review, we described the relationship between oxidative stress and circRNAs, the circRNAs related to oxidative stress, and the role of circRNAs in promoting or inhibiting the occurrence and development of diseases associated with the oxidative stress system.