AUTHOR=Chen Weilin , Wang Qi , Zhou Bin , Zhang Lihua , Zhu Honglin 

TITLE=Lipid Metabolism Profiles in Rheumatic Diseases

JOURNAL=Frontiers in Pharmacology

VOLUME=12

YEAR=2021

URL=https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2021.643520

DOI=10.3389/fphar.2021.643520

ISSN=1663-9812

ABSTRACT=<p>Rheumatic diseases are a group of chronic autoimmune disorders that involve multiple organs or systems and have high mortality. The mechanisms of these diseases are still ill-defined, and targeted therapeutic strategies are still challenging for physicians. Recent research indicates that cell metabolism plays important roles in the pathogenesis of rheumatic diseases. In this review, we mainly focus on lipid metabolism profiles (dyslipidaemia, fatty acid metabolism) and mechanisms in rheumatic diseases and discuss potential clinical applications based on lipid metabolism profiles.</p>