This article is a correction to:
Vitamin B12 Enhances Nerve Repair and Improves Functional Recovery After Traumatic Brain Injury by Inhibiting ER Stress-Induced Neuron Injury
Fangfang Wu1,2†
Ke Xu3†
Lei Liu1†
Kairui Zhang1Leilei Xia4
Man Zhang1Chenhuai Teng1Heyan Tong2Yifang He2Yujie Xue2Hongyu Zhang2
Daqing Chen1*Aiping Hu1,2*- 1Department of Emergency, The Second Affiliated Hospital and Yuying Children’s Hospital, Wenzhou Medical University, Wenzhou, China
- 2School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, China
- 3Institute of Life Sciences, Wenzhou University, Wenzhou, China
- 4Department of Emergency, Wenzhou People’s Hospital, The Third Clinical Institute Affiliated to Wenzhou Medical University, Wenzhou, China
A corrigendum on
by Wu, F., Xu K., Liu, L., Zhang, K.-R., Xia, L.-L., Zhang, M., Teng, C.-H., Tong, H.-Y., He, Y.-F., Xue, Y.-J., Zhang, H.-Y., Chen, D.-Q., Hu, A.-P. (2019). Front. Pharmacol. 10, 406. doi:10.3389/fphar.2019.00406
In the original article, there was a mistake in Figure 4P as published. The corrected Figure 4 appear below.
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way.
FIGURE 4
FIGURE 4. Vitamin B12 inhibits microtubule damage through ER stress after TBI. (A) Representative western blots of the expression of MAP-2, Tau. (B, C) Quantification from (A).##p < 0.01, #p < 0.05 vs. the sham group. *p < 0.05, && p < 0.01 vs. the TBI group. **p < 0.01 vs. the indicated group. Values represent the mean ± SEM, n = 5. (D) Representative fluorescent images depicting MAP-2 (green) with NeuN (red) in the cortex after TBI. Scale bar = 50 μm, scale bar = 10 µm. (E) Representative fluorescent images depicting Ace-tubulin(green) with Tyr-tubulin(red) in the PC 12 cells. Scale bar = 20 µm. (F) Representative western blots of the expression of IRE1α, GRP78, XBP-1, Chop, Cleaved-cas12. (G–K) Quantification from (F)*p < 0.05, **p < 0.01 and ***p < 0.001 vs. the indicated group. Values represent the mean ± SEM, n = 4. (L) Representative western blots of the expression of MAP-2, Ace-tubulin. (M–N) Quantification from (L).*p < 0.05 vs. the indicated group. Values represent the mean ± SEM, n = 4. (O) Representative fluorescent images depicting Ace-tubulin(green) with Tyr-tubulin(red) in the PC 12 cells. Scale bar = 20 µm. (P). Representative fluorescent images depicting MAP-2 (green) in vivo. Scale bar = 50 µm.
Keywords: vitamin B12, traumatic brain injury, endoplasmic reticulum stress, microtubule, myelin
Citation: Wu F, Xu K, Liu L, Zhang K, Xia L, Zhang M, Teng C, Tong H, He Y, Xue Y, Zhang H, Chen D and Hu A (2021) Corrigendum: Vitamin B12 Enhances Nerve Repair and Improves Functional Recovery After Traumatic Brain Injury by Inhibiting ER Stress-Induced Neuron Injury. Front. Pharmacol. 12:598335. doi: 10.3389/fphar.2021.598335
Received: 24 August 2020; Accepted: 22 February 2021;
Published: 12 April 2021.
Edited and reviewed by:
Nicholas M. Barnes, University of Birmingham, United KingdomCopyright © 2021 Wu, Xu, Liu, Zhang, Xia, Zhang, Teng, Tong, He, Xue, Zhang, Chen and Hu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Daqing Chen, Y2RxMTk2NUAxMjYuY29t; Aiping Hu, aGFwQHdtdS5lZHUuY24=
†These authors contributed equally to this work