AUTHOR=Annunziata Anna , Lanza Maurizia , Coppola Antonietta , Andreozzi Paolo , Spinelli Sara , Fiorentino Giuseppe TITLE=Alpha-1 Antitrypsin Deficiency: Home Therapy JOURNAL=Frontiers in Pharmacology VOLUME=12 YEAR=2021 URL=https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2021.575402 DOI=10.3389/fphar.2021.575402 ISSN=1663-9812 ABSTRACT=

While available in only a few countries, home therapy is a possible strategy for the treatment of alpha-1 antitrypsin deficiency. We want to describe our experience in the management of human alpha-1 antitrypsin using home care intravenous augmentation therapy during this emergency period caused by SARS-CoV2 infection. We assessed the safety of the home treatment and the quality of life of patients enrolled in the program.