AUTHOR=Wu Qing , Liu Xia , Zhu Lin , Zhu Yichen , Mei Tingting , Cao Shanshan , Shen Yan , Ding Jun , Lin Tan 

TITLE=Clinical Assessment of Ultrasound-Guided Local Lauromacrogol Injection Combined With Curettage and Hysteroscopy for Cesarean Scar Pregnancy

JOURNAL=Frontiers in Pharmacology

VOLUME=11

YEAR=2020

URL=https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2020.601977

DOI=10.3389/fphar.2020.601977

ISSN=1663-9812

ABSTRACT=<p><bold>Background:</bold> To evaluate the efficacy, safeness and cost of ultrasound-guided local lauromacrogol injection (USG-LLI) combined with curettage and hysteroscopy for cesarean scar pregnancy (CSP).</p><p><bold>Methods:</bold> This was a retrospective study included 151 CSP patients diagnosed with CSP from June 2017 to December 2019, and treated by USG-LLI (<italic>n</italic> = 86) or uterine artery embolization (UAE) (<italic>n</italic> = 65) combined with curettage and hysteroscopy. Clinical data and outcome were analyzed.</p><p><bold>Results:</bold> There were no significant differences in basic clinical characteristics in the two groups. Two groups showed the similar success rates. USG-LLI group, compared with UAE group had significantly lower complication rates (9.30 vs. 44.62%), lower total costs (both medical and non-medication cost) (<italic>p</italic> &lt; 0.05).</p><p><bold>Conclusions:</bold> USG-LLI combined with curettage and hysteroscopy is a feasible method to treat CSP with minimal invasion and high efficacy. Moreover, compared with curettage after UAE, USG-LLI exhibited lower complication rate and required fewer expenses.</p>