AUTHOR=He Ying-hua , Tian Guo 

TITLE=Autophagy as a Vital Therapy Target for Renal Cell Carcinoma

JOURNAL=Frontiers in Pharmacology

VOLUME=11

YEAR=2021

URL=https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2020.518225

DOI=10.3389/fphar.2020.518225

ISSN=1663-9812

ABSTRACT=<p>Autophagy is a process that degrades and recycles superfluous organelles or damaged cellular contents. It has been found to have dual functions in renal cell carcinoma (RCC). Many autophagy-related proteins are regarded as prognostic markers of RCC. Researchers have attempted to explore synthetic and phytochemical drugs for RCC therapy that target autophagy. In this review, we highlight the importance of autophagy in RCC and potential treatments related to autophagy.</p>