AUTHOR=Suvarna Vasanti , Sarkar Megha , Chaubey Pramila , Khan Tabassum , Sherje Atul , Patel Kavitkumar , Dravyakar Bhushan TITLE=Bone Health and Natural Products- An Insight JOURNAL=Frontiers in Pharmacology VOLUME=9 YEAR=2018 URL=https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2018.00981 DOI=10.3389/fphar.2018.00981 ISSN=1663-9812 ABSTRACT=

Bone metabolism involves a complex balance between matrix deposition, mineralization, and resorption. Numerous evidences have revealed that dietary components and phytoconstituents can influence these processes, through inhibition of bone resorption, thus exhibiting beneficial effects on the skeleton. Various traditional herbal formulae in ayurvedic and Chinese medicine have shown demonstrable benefits in pharmacological models of osteoporosis. The present review discusses normal bone metabolism and disorders caused by bone disruption, with particular reference to osteoporosis and current therapeutic treatment. Furthermore the effects of constituents from natural products on bone tissue are explained, with relevant evidences of efficacy in various experimental models.