AUTHOR=Yuan Dong-Sheng , Chen Yan-Ping , Tan Li-Li , Huang Shui-Qing , Li Chang-Qing , Wang Qi , Zeng Qing-Ping 

TITLE=Artemisinin: A Panacea Eligible for Unrestrictive Use?

JOURNAL=Frontiers in Pharmacology

VOLUME=8

YEAR=2017

URL=https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2017.00737

DOI=10.3389/fphar.2017.00737

ISSN=1663-9812

ABSTRACT=<p>Although artemisinin has been used as anti-malarial drug, accumulating evidence on the extended therapeutic potential of artemisinin emerges. Apart from anti-malaria and anti-tumor, artemisinin can also exert beneficial effects on some metabolic disorders, such as obesity, diabetes, and aging-related diseases. However, whether artemisinin should be applied to treatment of the wide-spectrum diseases is debating. Here, we discuss the predisposition of a raised risk of malarial resistance to artemisinin from consideration of the multi-target and non-specific features of artemisinin.</p>