Antioxidant Effect of Fructus Ligustri Lucidi Aqueous Extract in Ovariectomized Rats Is Mediated through Nox4-ROS-NF-κB Pathway
- 1Cell and Biochemistry Lab, Preclinical Medicine School, Beijing University of Chinese Medicine, Beijing, China
- 2Chinese Material Medica School, Beijing University of Chinese Medicine, Beijing, China
- 3Modern Research Center for TCM, Beijing University of Chinese Medicine, Beijing, China
- 4The First Affiliated Hospital of He'nan TCM University, Zhengzhou, Henan, China
- 5Diabetes Research Center, Beijing University of Chinese Medicine, Beijing, China
- 6The Research Institute of McGill University Health Center, Montreal, QC, Canada
- 7Oral Biological Medicinal Science, University of British Columbia, Vancouver, BC, Canada
A corrigendum on
Antioxidant Effect of Fructus Ligustri Lucidi Aqueous Extract in Ovariectomized Rats Is Mediated through Nox4-ROS-NF-κB Pathway
by Wang, L., Ma, R., Guo, Y, Sun, J., Liu, H., Zhu, R., et al. (2017). Front. Pharmacol. 8:266. doi: 10.3389/fphar.2017.00266
In the original article, there was a mistake in Figure 4. The representative images of immunohistochemical staining (A–D; sections were counterstained with hematoxylin; original magnification, X20), and western blot assays (E, F) showed that FLL treatment decreased Nox4 expression in tibias and uteri of OVX rats (n = 9). In addition, FLL treatment also decreased cytochrome C (Cyto-C; G) and increased Bcl-2 expression (H) in the tibias of OVX rats as published. The images of the western blot in the Figure 4G were carelessly repeated with Figure 4H. The corrected Figure 4G appears below. The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way.
Statistical analysis: The results were expressed as mean ± SD. One-way ANOVA test was performed between multiple groups when homogeneity of variance and normality were met using SPSS software (Version 20.0). Otherwise, Dunnett's T3 and nonparametric tests were conducted between multiple groups, respectively. A value of p < 0.05 was considered to be statistical difference.
Conflict of Interest Statement
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Keywords: Fructus Ligustri Lucidi, ovariectomy, NADPH oxidase 4 (Nox4), nuclear factor kappa B (NF-κB), oxidative stress
Citation: Wang L, Ma R, Guo Y, Sun J, Liu H, Zhu R, Liu C, Li J, Li L, Chen B, Sun L, Tang J, Zhao D, Mo F, Niu J, Jiang G, Fu M, Brömme D, Zhang D and Gao S (2017) Corrigendum: Antioxidant Effect of Fructus Ligustri Lucidi Aqueous Extract in Ovariectomized Rats Is Mediated through Nox4-ROS-NF-κB Pathway Front. Pharmacol. 8:590. doi: 10.3389/fphar.2017.00590
Received: 01 July 2017; Accepted: 15 August 2017;
Published: 25 August 2017.
Edited and reviewed by: Kalin Yanbo Zhang, University of Hong Kong, Hong Kong
Copyright © 2017 Wang, Ma, Guo, Sun, Liu, Zhu, Liu, Li, Li, Chen, Sun, Tang, Zhao, Mo, Niu, Jiang, Fu, Brömme, Zhang and Gao. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Dongwei Zhang, ZG9uZ3dlaTEwMDZAZ21haWwuY29t
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†These authors have contributed equally to this work.