AUTHOR=Chagas Vinicyus Teles , França Lucas Martins , Malik Sonia , Paes Antonio Marcus de Andrade 

TITLE=Syzygium cumini (L.) skeels: a prominent source of bioactive molecules against cardiometabolic diseases

JOURNAL=Frontiers in Pharmacology

VOLUME=6

YEAR=2015

URL=https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2015.00259

DOI=10.3389/fphar.2015.00259

ISSN=1663-9812

ABSTRACT=<p><italic>Syzygium cumini</italic> (Myrtaceae) is a worldwide medicinal plant traditionally used in herbal medicines due to its vaunted properties against cardiometabolic disorders, which include: antihyperglycemic, hypolipemiant, antiinflammatory, cardioprotective, and antioxidant activities. These properties have been attributed to the presence of bioactive compounds such as phenols, flavonoids, and tannins in different parts of the plant, albeit the knowledge on their mechanisms of action is scarce. This mini-review highlights the cardiometabolic properties of <italic>S. cumini</italic> by correlating its already identified phytochemicals with their described mechanisms of action. Data herein compiled show that some compounds target multiple metabolic pathways; thereby, becoming potential pharmacological tools. Moreover, the lack of clinical trials on <italic>S. cumini</italic> usage makes it a fruitful field of interest for both scientific community and pharmaceutical industry.</p>