AUTHOR=Lu Juan , Qin Jia-zhang , Chen Ping , Zhao Si-jia 

TITLE=Quality Difference Study of Six Varieties of Ganoderma lucidum with Different Origins

JOURNAL=Frontiers in Pharmacology

VOLUME=3

YEAR=2012

URL=https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2012.00057

DOI=10.3389/fphar.2012.00057

ISSN=1663-9812

ABSTRACT=<p>The quality difference of six varieties <italic>Ganoderma lucidum</italic> with different origins was investigated in this study by comparing the contents of ganoderic acid A and B, polysaccharide, and triterpenoids. The contents of ganoderic acid A and B in <italic>G. lucidum</italic> were analyzed by ultra performance liquid chromatography (UPLC). There was higher content of ganoderic acid A in <italic>G. lucidum</italic> of Dabie Mountain and Longquan. The <italic>G. lucidum</italic> from Longquan has the highest content of ganoderic acid B. The content of polysaccharide was determined by Anthrone–sulfuric acid method. The highest of polysaccharide content is <italic>G. lucidum</italic> from Liaocheng. The content of triterpenoid in <italic>G. lucidum</italic> was quantified by ultraviolet spectrophotometer at 548.1 nm using Ursolic acid as standard. The <italic>G. lucidum</italic> from Dabie Mountain has the highest content of triterpenoids. In summary, the content of ganoderic acid A and B, polysaccharide, and triterpenoids in <italic>G. lucidum</italic> with different origins are remarkably different, which may be caused by the conditions of cultivation and geographic environment.</p>