AUTHOR=Golbidi Saeid , Laher Ismail 

TITLE=Bladder Dysfunction in Diabetes Mellitus

JOURNAL=Frontiers in Pharmacology

VOLUME=1

YEAR=2010

URL=https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2010.00136

DOI=10.3389/fphar.2010.00136

ISSN=1663-9812

ABSTRACT=<p>Diabetic cystopathy is a well-recognized complication of diabetes mellitus, which usually develops in middle-aged or elderly patients with long-standing and poorly controlled disease. It may have broad spectrum clinical presentations. Patients may be asymptomatic, or have a wide variety of voiding complaints from overactive bladder and urge incontinence to decreased bladder sensation and overflow incontinence. This review focuses on pathophysiological mechanisms responsible for urologic complications of diabetes and emphasizing on recent developments in our understanding of this condition. We also tried to shed some light on therapeutic modalities like behavioral, pharmacological, and surgical approaches.</p>