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ORIGINAL RESEARCH article
Front. Pediatr.
Sec. Pediatric Immunology
Volume 13 - 2025 | doi: 10.3389/fped.2025.1571556
Analysis of the characteristics of blood inflammatory cytokines and their influencing factors in acute exacerbations of allergic asthma in children
Provisionally accepted- Yuhuan People's Hospital, Taizhou, China
Background: Exploring the characteristics of serum inflammatory cytokine changes during acute exacerbations of pediatric allergic asthma, and analyzing factors influencing poor asthma control and predictive indicators.Methods: Forty children with acute exacerbations of allergic asthma, either outpatients or inpatients, were selected as the observation group, and forty healthy children undergoing physical examinations during the same period served as the control group. Flow cytometry was used to analyze the characteristics of blood inflammatory cytokines in both groups. Logistic multiple regression was used to analyze the influencing factors of poor asthma control, and ROC curve analysis was used to evaluate the indicators for predicting poor asthma control.
Keywords: Allergic Asthma, cytokine, Children, macrophage, respiratory infection, Inhaled corticosteroids (ICS), Subcutaneous Specific Allergen Immunotherapy (SCIT)
Received: 05 Feb 2025; Accepted: 24 Mar 2025.
Copyright: © 2025 Shen, Yang, Zhou and Li. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Ren Shen, Yuhuan People's Hospital, Taizhou, 317602, China
Shanpu Yang, Yuhuan People's Hospital, Taizhou, 317602, China
Yan Zhou, Yuhuan People's Hospital, Taizhou, 317602, China
Jinɡjinɡ Li, Yuhuan People's Hospital, Taizhou, 317602, China
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