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CASE REPORT article
Front. Pediatr.
Sec. Pediatric Surgery
Volume 13 - 2025 | doi: 10.3389/fped.2025.1525530
This article is part of the Research TopicInnovative Approaches in Pediatric Surgical Oncology Volume IIView all 7 articles
High-grade Appendiceal Mucinous Neoplasms in Children: a case report
Provisionally accepted- 1The Affiliated Hospital of Qingdao University, Qingdao, China
- 2Qingdao Women and Children's Hospital, Qingdao, Shandong Province, China
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Background :Appendiceal Mucinous Neoplasms (AMNs) are a rare disease characterized by the accumulation of mucus within the vermiform appendix and are frequently misdiagnosed as appendicitis. Hence, it is crucial to consider AMNs because they have the potential to progress into peritoneal pseudomyxoma (PP), a clinical syndrome distinguished by mucus buildup in the peritoneum leading to progressive abdominal pathology. Case report:We present a case involving a 13-year-old male patient who was initially suspected of having acute purulent appendicitis prior to surgery, a formal laparoscopic appendectomy was performed. Microscopic examination revealed the presence of high-grade appendiceal mucinous neoplasm (HAMN), with certain areas exhibiting features consistent with mucinous adenocarcinoma, and focal invasion of the muscular layer was observed. After multidisciplinary discussion, the patient underwent laparoscopic ileocecal resection followed by hyperthermic intraperitoneal chemotherapy (HIPEC) and molecular targeted therapy leading to favorable outcome during subsequent regular follow-up evaluations validating the appropriateness of the chosen surgical procedure.Conclusion:This case presents a rare pediatric appendiceal mucinous tumor, highlighting the importance of recognizing the presence of a tumor for clinicians when diagnosing an appendiceal abscess.
Keywords: appendiceal mucinous neoplasms, Appendicitis, Pediatrics, Surgery, case report
Received: 09 Nov 2024; Accepted: 08 Apr 2025.
Copyright: © 2025 Wang, Zhang, Hao, Lu, Li and Shang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Cong Shang, The Affiliated Hospital of Qingdao University, Qingdao, China
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