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ORIGINAL RESEARCH article

Front. Pediatr.
Sec. Children and Health
Volume 13 - 2025 | doi: 10.3389/fped.2025.1519017
This article is part of the Research Topic Non-Invasive Imaging Techniques In Children: Clinical Applications and Advances View all articles

The Consistency and Efficacy of Optical Coherence Tomography for Evaluation Ocular Torsion Angle in Children

Provisionally accepted
Rongjun Liu Rongjun Liu Jingjing Zhao Jingjing Zhao Kaili Yu Kaili Yu Dehai Zhu Dehai Zhu *
  • First Hospital, Peking University, Beijing, China

The final, formatted version of the article will be published soon.

    To explore the consistency and efficacy of optical coherence tomography (OCT) for evaluation ocular torsion angle when comparing to fundus photography in children. Method: Patients who had undergone fundus photography and OCT in one day were included in this study. The fundus photography was taken by fundus camera and then imported into the Adobe Photoshop 2021 software. The fovea-disc angle (FDA) was calculated manually. The OCT was used to automatically detect the centers of the optic disc and fovea, and then the software calculates the FDA on the same device.The mean and range of variables were calculated in this study. Group differences were assessed using the paired t-test. Statistical significance was determined when P values were <0.05.Bland-Altman plots were constructed to verify the agreement of FDA measured by fundus and OCT. Results:A total of 100 patients were included and objective measurements of the ocular torsion angle via OCT and fundus photography were similar. The mean FDA of 32 patients aged 2-6 years old was -7.84±4.67°via fundus and -6.71±6.19°via OCT. The mean FDA of 68 patients aged 6-18 years old was -8.47±5.22°via fundus and -8.97±5.41°via OCT. According to the ROC curves of the FDA for diagnosing ocular extorsion. The AUC was greatest for OCT (0.943, 95% CI: 0.902 to 0.984), followed by fundus photography (0.92, 95%CI: 0.86 to 0.979). With the Youden method, the optimal cut-off point for diagnosing ocular extorsion with OCT was -6.35°, OCT demonstrated a sensitivity of 100%, as specificity of 49.2%. Besides, the optimal cut-off point for diagnosing ocular extorsion with fundus photography was -6.5°.

    Keywords: Ocular torsion angle, OCT, Fundus, Children, Strabismus

    Received: 29 Oct 2024; Accepted: 13 Jan 2025.

    Copyright: © 2025 Liu, Zhao, Yu and Zhu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Dehai Zhu, First Hospital, Peking University, Beijing, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.