AUTHOR=Chen Henry , Numis Adam L. , Shellhaas Renée A. , Mytinger John R. , Samanta Debopam , Singh Rani K. , Hussain Shaun A. , Takacs Danielle , Knupp Kelly G. , Shao Li-Rong , Stafstrom Carl E. TITLE=Treatment efficacy for infantile epileptic spasms syndrome in children with trisomy 21 JOURNAL=Frontiers in Pediatrics VOLUME=13 YEAR=2025 URL=https://www.frontiersin.org/journals/pediatrics/articles/10.3389/fped.2025.1498425 DOI=10.3389/fped.2025.1498425 ISSN=2296-2360