REVIEW article

Front. Pediatr.

Sec. Pediatric Nephrology

Volume 13 - 2025 | doi: 10.3389/fped.2025.1407437

This article is part of the Research TopicInsights in Pediatric NephrologyView all 9 articles

Pediatric Renal Abscess: Clinical Analysis and Literature Review

Provisionally accepted
Jianxin  SunJianxin Sun1Lina  ShiLina Shi2Lezhen  YeLezhen Ye1Yanan  XuYanan Xu3*
  • 1Department of Pediatrics, Ningbo Women and Children's Hospital, Ningbo, China
  • 2Yuyao People's Hospital, Yuyao, Zhejiang, China
  • 3Ningbo Women and Children's Hospital, Ningbo, Zhejiang, China

The final, formatted version of the article will be published soon.

Background: Pediatric renal abscesses is a severe infectious disease with a long treatment period. Due to atypical symptoms, there is a risk of delayed diagnosis, missed diagnosis, and misdiagnosis. Inadequate or incomplete treatment can lead to prolonged hospital stays, even Irreversible kidney damage. This study aimed to analyze the clinical characteristics of pediatric renal abscesses, aiming for early diagnosis and timely, appropriate treatment.A retrospective analysis was conducted on clinical manifestations, laboratory tests, imaging studies, and treatment data of 12 pediatric renal abscess cases treated in the Nephrology Department of our hospital from October 2018 to March 2023. Results: Among the 12 cases, there were 3 males and 9 females, aged between 7 months to 12 years. All cases were from urban areas, with fever being the primary symptom (100%), accompanied in some by abdominal pain and urinary frequency/pain. Clinical symptoms were atypical, with 91%showing elevated white blood cell count(WBC), a significant rise in neutrophil percentage, Creactive protein (CRP), and a marked increase in procalcitonin (100%). significant elevation of urinary white blood cells in 83.3% of cases. Both urine and blood cultures were negative. All 12 cases underwent abdominal CT or Magnetic Resonance Urography (MRU), showing abscesses, all less than 3cm. Treatment included third-generation cephalosporins, with the addition of linezolid in cases where the initial treatment was ineffective. Hospital stays ranged from 10 to 21 days. Follow-up MRU showed the disappearance of abscesses.Clinical symptoms of pediatric renal abscesses are atypical. Children with fever, accompanied by abdominal pain, and significant elevation in white blood cells, CRP, and PCT should be considered for renal abscess, and abdominal CT or MRU is recommended for early diagnosis. Conservative anti-infection treatment can yield good results for abscesses smaller than 3cm.

Keywords: Renal, Abscess, pediatric, Management, review

Received: 26 Mar 2024; Accepted: 14 Apr 2025.

Copyright: © 2025 Sun, Shi, Ye and Xu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Yanan Xu, Ningbo Women and Children's Hospital, Ningbo, 315012, Zhejiang, China

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